Journal of Materials Science: Materials in Medicine

, 19:3345

Dissolution characteristics of extrusion freeformed hydroxyapatite–tricalcium phosphate scaffolds

  • H. Y. Yang
  • I. Thompson
  • S. F. Yang
  • X. P. Chi
  • J. R. G. Evans
  • R. J. Cook
Article

DOI: 10.1007/s10856-008-3473-7

Cite this article as:
Yang, H.Y., Thompson, I., Yang, S.F. et al. J Mater Sci: Mater Med (2008) 19: 3345. doi:10.1007/s10856-008-3473-7

Abstract

The dissolution behaviour of calcium phosphate filaments made by extrusion freeforming for hard tissue scaffolds was measured. The solubility of filaments with different HA/β-TCP ratios sintered at temperatures from 1,100 to 1,300°C was measured under simulated physiological conditions (tris buffer solution: tris(hydroxyl) methyl–aminomethane–HCl), pH 7.4, 37°C). Calcium and phosphate concentrations were measured separately by inductively coupled plasma (ICP) atomic emission spectroscopy. Surface morphologies and composition before and after immersion were analyzed by SEM and EDS. The results clearly show that as the β-TCP content increased, the dissolution increased. Higher sintering temperatures, with consequent closure of surface pores, resulted in lower dissolution. Examination of the surface suggested dissolution on preferred sites by pitting.

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • H. Y. Yang
    • 1
  • I. Thompson
    • 2
  • S. F. Yang
    • 1
  • X. P. Chi
    • 1
  • J. R. G. Evans
    • 3
  • R. J. Cook
    • 2
  1. 1.Department of MaterialsQueen Mary, University of LondonLondonUK
  2. 2.GKT Dental InstituteKings CollegeLondonUK
  3. 3.Department of ChemistryUniversity College LondonLondonUK