Article

Journal of Interventional Cardiac Electrophysiology

, Volume 25, Issue 3, pp 229-234

First online:

Ventricular tachycardia inducibility after radiofrequency ablation affects the outcomes in patients with coronary artery disease and implantable cardioverter-defibrillators: The role of left ventricular function

  • Andrea ColellaAffiliated withDepartment Heart and Vessels, University of FlorenceLaboratorio di Elettrofisiologia, Azienda Ospedaliero-Universitaria di Careggi Email author 
  • , Marzia GiaccardiAffiliated withDepartment Cardiovascular Rehabilitation, Don Gnocchi Foundation
  • , Raffaele Molino LovaAffiliated withDepartment Cardiovascular Rehabilitation, Don Gnocchi Foundation
  • , Carmine LiccardiAffiliated withDepartment Heart and Vessels, University of Florence
  • , Gian Franco GensiniAffiliated withDepartment Heart and Vessels, University of FlorenceDepartment Cardiovascular Rehabilitation, Don Gnocchi Foundation

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Purpose

We hypothesized that inducibility of the VT responsible for ICD therapies at the end of RFCA, would also be associated with a differential risk, depending on left ventricular function.

Methods

We retrospectively studied 66 patients with previous myocardial infarction and with ICD who also underwent RFCA for recurrent refractory VTs.

Results

During the follow-up only 19 patients (29%) showed VTs. Among patients with ejection fraction (EF) ≤ 35%, 11 out of 25 still continued to have VT recurrences, independent of the inducibility of the VT. Among patients with EF >35% and <50%, no recurrent VT was any longer detected in the nine patients in whom the VT was not inducible, while VT recurrences still continued only in the eight patients in whom it was. Finally, all the 24 patients with EF ≥50% did not show any recurrent VT.

Conclusions

Our findings confirm the role of RFCA in reducing ICD therapies and also place RFCA in the overall clinical management of recurrent post infarction VTs according to the left ventricular function.

Keywords

Sudden death Ventricular tachycardia Implantable defibrillators Catheter ablation Ejection fraction