Journal of Interventional Cardiac Electrophysiology

, Volume 25, Issue 3, pp 229–234

Ventricular tachycardia inducibility after radiofrequency ablation affects the outcomes in patients with coronary artery disease and implantable cardioverter-defibrillators: The role of left ventricular function

  • Andrea Colella
  • Marzia Giaccardi
  • Raffaele Molino Lova
  • Carmine Liccardi
  • Gian Franco Gensini
Article

DOI: 10.1007/s10840-008-9351-x

Cite this article as:
Colella, A., Giaccardi, M., Lova, R.M. et al. J Interv Card Electrophysiol (2009) 25: 229. doi:10.1007/s10840-008-9351-x
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Abstract

Purpose

We hypothesized that inducibility of the VT responsible for ICD therapies at the end of RFCA, would also be associated with a differential risk, depending on left ventricular function.

Methods

We retrospectively studied 66 patients with previous myocardial infarction and with ICD who also underwent RFCA for recurrent refractory VTs.

Results

During the follow-up only 19 patients (29%) showed VTs. Among patients with ejection fraction (EF) ≤ 35%, 11 out of 25 still continued to have VT recurrences, independent of the inducibility of the VT. Among patients with EF >35% and <50%, no recurrent VT was any longer detected in the nine patients in whom the VT was not inducible, while VT recurrences still continued only in the eight patients in whom it was. Finally, all the 24 patients with EF ≥50% did not show any recurrent VT.

Conclusions

Our findings confirm the role of RFCA in reducing ICD therapies and also place RFCA in the overall clinical management of recurrent post infarction VTs according to the left ventricular function.

Keywords

Sudden deathVentricular tachycardiaImplantable defibrillatorsCatheter ablationEjection fraction

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Andrea Colella
    • 1
    • 3
  • Marzia Giaccardi
    • 2
  • Raffaele Molino Lova
    • 2
  • Carmine Liccardi
    • 1
  • Gian Franco Gensini
    • 1
    • 2
  1. 1.Department Heart and VesselsUniversity of FlorenceFlorenceItaly
  2. 2.Department Cardiovascular RehabilitationDon Gnocchi FoundationFlorenceItaly
  3. 3.Laboratorio di ElettrofisiologiaAzienda Ospedaliero-Universitaria di CareggiFlorenceItaly