Journal of Interventional Cardiac Electrophysiology

, Volume 17, Issue 2, pp 103–109

Pulmonary vein isolation and linear lesions in atrial fibrillation ablation

Authors

  • Imran Sheikh
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • David Krum
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • Ryan Cooley
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • Anwer Dhala
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • Zalmen Blanck
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • Atul Bhatia
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • Vikram Nangia
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
  • Masood Akhtar
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
    • Electrophysiology Laboratories, Aurora Sinai/Aurora St. Luke’s Medical CentersUniversity of Wisconsin School of Medicine and Public Health
Article

DOI: 10.1007/s10840-006-9066-9

Cite this article as:
Sheikh, I., Krum, D., Cooley, R. et al. J Interv Card Electrophysiol (2006) 17: 103. doi:10.1007/s10840-006-9066-9

Abstract

Background

Various strategies have been used for atrial fibrillation (AF) ablation. It is unclear whether adding linear lesions to pulmonary vein (PV) isolation has significant advantages.

Objectives

We assessed the clinical benefit of adding linear lesions in patients undergoing PV isolation for AF.

Methods

One hundred patients (63 male and 37 female; mean age of 59 ± 11 years) with documented paroxysmal AF were included in the study. Patients were randomized into two groups. The first group underwent PV isolation alone. The second group underwent PV isolation and had two linear lesions created; one line between the superior PVs, and a second line from the left inferior PV to the mitral valve annulus. Patients’ clinical progress after the ablation was evaluated and compared at 1, 3, and 9 months after their respective ablation procedures.

Results

The linear lesions group maintained sinus rhythm and had fewer symptoms than the lone PV isolation group (86 vs. 58%, respectively) (p < 0.05) at 1 month. At 9 months, when patients who reverted to AF underwent additional management to regain sinus rhythm (90 vs. 82%, respectively) (p = NS), there was no statistical difference between the groups regarding the use of antiarrhythmics, the need for electrical cardioversion, and subjective improvement.

Conclusion

The addition of linear lesions to PV isolation more effectively achieved sinus rhythm initially and fewer patients required additional management to maintain their rhythm when compared to patients who underwent lone PV isolation. However, at 9 months, the overall results were similar in both groups.

Keywords

Atrial fibrillationAblation proceduresPulmonary vein isolationLinear lesions
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Copyright information

© Springer Science+Business Media, LLC 2007