Journal of Computational Electronics

, Volume 6, Issue 1, pp 363-365

Shockley-Ramo theorem measures conformation changes of ion channels and proteins

  • Bob EisenbergAffiliated withDepartment of Molecular Biophysics, Rush University Medical Center Email author 
  • , Wolfgang NonnerAffiliated withMiller School of Medicine, University of Miami

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Theorems are rarely used in biology because they rarely help the descriptive experimentation to which biologists are devoted. A generalization of Kirchoff’s current law—the Shockley-Ramo (SR) theorem [1–6]—seems an exception. SR allows interpretation of macroscopic scale ‘gating’ currents associated with atomic scale charge movements within proteins.


Ion channels Shockley-Ramo Gating current