Clinical outcomes of elective single morula embryo transfer versus elective single blastocyst embryo transfer in IVF-ET
- Sang Min KangAffiliated withMaria Fertility Clinic
- , Sang Won LeeAffiliated withMaria Fertility Clinic
- , Hak Jun JeongAffiliated withMaria Fertility Clinic
- , San Hyun YoonAffiliated withSeoul Maria Fertility Hospital
- , Min Whan KohAffiliated withDepartment of Obstetrics and Gynecology, College of Medicine, Yeungnam University
- , Jin Ho LimAffiliated withSeoul Maria Fertility Hospital
- , Seong Goo LeeAffiliated withMaria Fertility Clinic Email author
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To compare the clinical outcomes of elective single morula embryo transfer (eSMET) versus elective single blastocyst embryo transfer (eSBET) in selected patients.
This study was a retrospective study which analyzed for 271 cycles in women under 37 years of age who are undergoing their first or second trial of in vitro fertilization-embryo transfer (IVF-ET) from January 2008 to December 2009. The eSMET was performed on day 4 (n = 130) and the eSBET was conducted on day 5 (n = 141).
The clinical pregnancy rate (51.5% vs. 51.8%, p = 0.97), implantation rate (52.3% vs. 52.5%, p = 0.98), and live birth rate (39.2% vs. 44.7%, p = 0.36) were similar in the eSMET and eSBET groups, respectively. The miscarriage rate of the eSMET group (23.9%) was slightly higher than that of the eSBET group (13.7%) (p = 0.12), without reaching statistical significance. There was only one case of monozygotic twin pregnancy in each group.
The clinical outcomes of day 4 eSMET were comparable to those of day 5 eSBET. Therefore, day 4 eSMET is a viable option or an alternative to day 5 eSBET, with no difference in success rates.
KeywordsElective single embryo transfer Morula Blastocyst Monozygotic twins Live birth
- Clinical outcomes of elective single morula embryo transfer versus elective single blastocyst embryo transfer in IVF-ET
Journal of Assisted Reproduction and Genetics
Volume 29, Issue 5 , pp 423-428
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- Print ISSN
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- Springer US
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- Elective single embryo transfer
- Monozygotic twins
- Live birth
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- Author Affiliations
- 1. Maria Fertility Clinic, Samsung Fire Bldg. 2-1 Beomeo-Dong 3, Suseong-Gu, Daegu, 706-743, Republic of Korea
- 2. Seoul Maria Fertility Hospital, 103-11 Shinseol-Dong, Dongdaemun-Gu, Seoul, 130-812, Republic of Korea
- 3. Department of Obstetrics and Gynecology, College of Medicine, Yeungnam University, 317-1 Daemyeong-5Dong, Nam-Gu, Daegu, 705-717, Republic of Korea