Journal of Assisted Reproduction and Genetics

, Volume 28, Issue 5, pp 415–418

The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

  • Laura Governini
  • Raoul Orvieto
  • Cristiana Guerranti
  • Laura Gambera
  • Vincenzo De Leo
  • Paola Piomboni
Assisted Reproduction Technologies

DOI: 10.1007/s10815-011-9548-2

Cite this article as:
Governini, L., Orvieto, R., Guerranti, C. et al. J Assist Reprod Genet (2011) 28: 415. doi:10.1007/s10815-011-9548-2

Abstract

In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R = 0.75; P < 0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p < 0.02) and number of embryos transferred (p < 0.02), compared to the PFC negative group.

Keywords

InfertilityIVFPFC contaminationFollicular fluid

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Laura Governini
    • 1
    • 2
  • Raoul Orvieto
    • 3
    • 4
  • Cristiana Guerranti
    • 5
  • Laura Gambera
    • 2
    • 6
  • Vincenzo De Leo
    • 2
    • 6
  • Paola Piomboni
    • 1
    • 2
    • 7
  1. 1.Department Biomedical Sciences, Applied Biology SectionUniversity of SienaSienaItaly
  2. 2.Center for Diagnosis and Treatment of Couple SterilityS. Maria alle Scotte HospitalSienaItaly
  3. 3.Infertility and IVF UnitBarzilai Medical CenterAshkelonIsrael
  4. 4.Ben Gurion University of the NegevBeer ShevaIsrael
  5. 5.Department Environmental Sciences “G.Sarfatti”University of SienaSienaItaly
  6. 6.Department Pediatrics, Obstetrics and Reproductive MedicineUniversity of SienaSienaItaly
  7. 7.Department of Biomedical Sciences, Biology Section, Center for the Diagnosis and Treatment of Couple Sterility, S. Maria alle Scotte HospitalUniversity of SienaSienaItaly