, Volume 28, Issue 5, pp 415-418

The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity

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Abstract

In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R = 0.75; P < 0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p < 0.02) and number of embryos transferred (p < 0.02), compared to the PFC negative group.

Capsule

Contamination with perfluorinated compounds decreases fertilization rate and the number of embryos transferred in patients undergoing IVF-ET cycles.