The impact of environmental exposure to perfluorinated compounds on oocyte fertilization capacity
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- Governini, L., Orvieto, R., Guerranti, C. et al. J Assist Reprod Genet (2011) 28: 415. doi:10.1007/s10815-011-9548-2
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In an attempt to assess the effect of perfluorinated compounds (PFC) on oocytes quality and fertilization rate, we studied follicular fluid (FF) PFC levels in 18 patients undergoing IVF-ET cycles. A significant correlation (R = 0.75; P < 0.001) was observed between FF PFC levels and fertilization rate. Moreover, patients with FF PFC contamination had significantly lower fertilization rate (p < 0.02) and number of embryos transferred (p < 0.02), compared to the PFC negative group.