Journal of Assisted Reproduction and Genetics

, Volume 27, Issue 9, pp 539–544

Overweight Men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles

  • Julia Keltz
  • Athena Zapantis
  • Sangita K. Jindal
  • Harry J. Lieman
  • Nanette Santoro
  • Alex J. Polotsky
Assisted Reproduction

DOI: 10.1007/s10815-010-9439-y

Cite this article as:
Keltz, J., Zapantis, A., Jindal, S.K. et al. J Assist Reprod Genet (2010) 27: 539. doi:10.1007/s10815-010-9439-y

Abstract

Purpose

To evaluate if elevated male body mass influences success after assisted reproductive technologies

Methods

Retrospective study of 290 cycles.

Results

Male body mass index greater than 25.0 kg/m2 was associated with significantly lower clinical pregnancy (53.2% vs. 33.6%). Multivariable logistic regression indicated that the likelihood of clinical pregnancy was decreased if the male partner was overweight after in vitro fertilization but not after intracytoplasmic sperm injection (odds ratios: 0.21 [0.07–0.69] vs. 0.75 [0.38–1.49], respectively) after adjustment for number of embryos transferred, sperm concentration, female age and body mass.

Conclusion

In this cohort, overweight status of the male partner was independently associated with decreased likelihood of clinical pregnancy after in vitro fertilization but not after intracytoplasmic sperm injection. A detrimental impact of higher male body mass was observed after adjusting for sperm concentration, suggesting that intracytoplasmic sperm injection may overcome some obesity related impairment of sperm-egg interaction.

Keywords

Male obesity In vitro fertilization IVF/ICSI outcome Assisted reproduction 

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Julia Keltz
    • 1
  • Athena Zapantis
    • 1
    • 2
  • Sangita K. Jindal
    • 1
    • 2
  • Harry J. Lieman
    • 1
    • 2
  • Nanette Santoro
    • 1
    • 2
    • 3
  • Alex J. Polotsky
    • 1
    • 2
  1. 1.Department of Obstetrics and Gynecology and Women’s HealthAlbert Einstein College of MedicineBronxUSA
  2. 2.Montefiore’s Institute for Reproductive Medicine and HealthAlbert Einstein College of Medicine and Montefiore Medical CenterBronxUSA
  3. 3.Department of Obstetrics and GynecologyUniversity of ColoradoDenverUSA

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