Overweight Men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles
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To evaluate if elevated male body mass influences success after assisted reproductive technologies
Retrospective study of 290 cycles.
Male body mass index greater than 25.0 kg/m2 was associated with significantly lower clinical pregnancy (53.2% vs. 33.6%). Multivariable logistic regression indicated that the likelihood of clinical pregnancy was decreased if the male partner was overweight after in vitro fertilization but not after intracytoplasmic sperm injection (odds ratios: 0.21 [0.07–0.69] vs. 0.75 [0.38–1.49], respectively) after adjustment for number of embryos transferred, sperm concentration, female age and body mass.
In this cohort, overweight status of the male partner was independently associated with decreased likelihood of clinical pregnancy after in vitro fertilization but not after intracytoplasmic sperm injection. A detrimental impact of higher male body mass was observed after adjusting for sperm concentration, suggesting that intracytoplasmic sperm injection may overcome some obesity related impairment of sperm-egg interaction.
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- Overweight Men: clinical pregnancy after ART is decreased in IVF but not in ICSI cycles
Journal of Assisted Reproduction and Genetics
Volume 27, Issue 9-10 , pp 539-544
- Cover Date
- Print ISSN
- Online ISSN
- Springer US
- Additional Links
- Male obesity
- In vitro fertilization
- IVF/ICSI outcome
- Assisted reproduction
- Industry Sectors
- Author Affiliations
- 1. Department of Obstetrics and Gynecology and Women’s Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Mazer Bldg, Room 322, Bronx, NY, USA
- 2. Montefiore’s Institute for Reproductive Medicine and Health, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, USA
- 3. Department of Obstetrics and Gynecology, University of Colorado, Denver, CO, 10461, USA