Journal of Assisted Reproduction and Genetics

, Volume 24, Issue 1, pp 11–15

Elective transfer of two embryos: Reduction of multiple gestations while maintaining high pregnancy rates

Authors

  • Donna Dowling-Lacey
    • The Jones Institute for Reproductive Medicine, Department of Obstetrics and GynecologyEastern Virginia Medical School
  • Estella Jones
    • The Jones Institute for Reproductive Medicine, Department of Obstetrics and GynecologyEastern Virginia Medical School
  • Jacob Mayer
    • The Jones Institute for Reproductive Medicine, Department of Obstetrics and GynecologyEastern Virginia Medical School
  • Silvina Bocca
    • The Jones Institute for Reproductive Medicine, Department of Obstetrics and GynecologyEastern Virginia Medical School
  • Laurel Stadtmauer
    • The Jones Institute for Reproductive Medicine, Department of Obstetrics and GynecologyEastern Virginia Medical School
    • The Jones Institute for Reproductive Medicine, Department of Obstetrics and GynecologyEastern Virginia Medical School
Assisted Reproduction

DOI: 10.1007/s10815-006-9085-6

Cite this article as:
Dowling-Lacey, D., Jones, E., Mayer, J. et al. J Assist Reprod Genet (2007) 24: 11. doi:10.1007/s10815-006-9085-6

Abstract

Purpose: To determine if the elective transfer of two embryos reduced the incidence of multiple gestations while maintaining high pregnancy rates. Methods: IVF patients and recipients of oocyte donation with an elective day-3 transfer of 2 or 3 embryos were studied. Result(s): In IVF, the elective transfer of 2 embryos resulted in similar pregnancy rate but significantly reduced the overall incidence of multiple gestations (20% versus 39%) when compared to the elective transfer of 3 embryos. Twin gestations decreased from 28% to 19%, and triplets significantly decreased from 9% to 1%. In oocyte donation, the elective transfer of 2 embryos resulted in similar pregnancy rate but also significantly reduced the overall incidence of multiple gestations (26% versus 48%), with twins decreasing from 34% to 24%, and with a significant reduction of triplets (13% versus 2%). Conclusions: In IVF and oocyte donation, the elective transfer of 2 embryos resulted in similar pregnancy rates and significantly reduced multiple gestation rates when compared to the elective transfer of 3 embryos.

Keywords

Embryo qualityImplantationIVFMultiple pregnanciesOocyte donation

Copyright information

© Springer Science+Business Media, LLC 2006