Assisted Reproduction

Journal of Assisted Reproduction and Genetics

, Volume 22, Issue 11, pp 401-405

First online:

Likelihood of natural conception following treatment by IVF

  • D. J. CahillAffiliated withUniversity of Bristol Centre for Reproductive Medicine, Academic Unit of Obstetrics and Gynaecology, Clinical Sciences at South Bristol, St. Michael's Hospital Email author 
  • , J. MeadowcroftAffiliated withUniversity of Bristol Centre for Reproductive Medicine
  • , V. A. AkandeAffiliated withUniversity of Bristol Centre for Reproductive Medicine, Academic Unit of Obstetrics and Gynaecology, Clinical Sciences at South Bristol, St. Michael's Hospital
  • , E. CorriganAffiliated withUniversity of Bristol Centre for Reproductive Medicine

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Abstract

Purpose: To predict the ongoing likelihood of natural conception, when a couple has ceased to try to conceive by assisted conception.

Methods: A postal questionnaire survey obtained information on further attempts to conceive and have a baby, either without treatment or by treatment elsewhere.

Results: From a response rate of 44%, there were 116 couples who fulfilled the study criteria. The data presented are based on this group. The overall likelihood of conception was 18%. Cumulative results were analysed up to 3 years following treatment. Univariate analysis showed that likelihood of conception was affected by infertility diagnosis (p = 0.024), woman's age (> 38 years; p < 0.005) (negatively) and duration of infertility (< 3 years; p < 0.005) (positively), while primary infertility did not. Effects of diagnosis and infertility duration were confirmed by multivariable analysis, controlling for age and primary infertility. These latter variables had no independent effect.

Conclusion: The likelihood of natural conception following IVF treatment was determined by duration of infertility and diagnosis; tubal disease in particular was associated with a very poor likelihood of natural conception.

Keywords

Assisted conception diagnostic classification failure to conceive fertility likelihood of natural conception