Journal of Autism and Developmental Disorders

, Volume 43, Issue 8, pp 1749–1757

Changing Concepts and Findings on Autism

Authors

    • MRC Social Genetic and Developmental Psychiatry Centre (SGDP), Institute of PsychiatryKing’s College London
Original Paper

DOI: 10.1007/s10803-012-1713-7

Cite this article as:
Rutter, M. J Autism Dev Disord (2013) 43: 1749. doi:10.1007/s10803-012-1713-7

Abstract

New research findings provide major challenges regarding our understanding of the concept of autism. These are critically discussed in relation to research relevant to classification, genetics, environmental risk factors, gene-environment interplay, animal models, biomarkers, clinical features, neuropathology, pharmacotherapy, behavioral treatments, and functioning in adult life. It is concluded that, although there have been major research advances; there is a need for a reconceptualization and an avoidance of claims that go beyond the evidence.

Keywords

Phenotypic overlap among disorders Genetic overlap Fractionable autism triad Broader autism phenotype Rett syndrome Epilepsy

Copyright information

© Springer Science+Business Media New York 2012