The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults
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- Geurts, H.M., Ridderinkhof, K.R. & Scholte, H.S. J Autism Dev Disord (2013) 43: 1630. doi:10.1007/s10803-012-1708-4
We tested whether in 85 healthy adults (18–29 years) there is a relationship between grey-matter (GM) volume and autism and ADHD symptom severity. The structural MRI findings and autism and ADHD self-reports revealed that autism and ADHD symptom severity was correlated with GM volume in the left inferior frontal gyrus. Autism symptom-severity was correlated with the left posterior cingulate, ADHD with the right parietal lobe, right temporal frontal cortex, bilateral thalamus, and left hippocampus/amygdala complex. Symptom severity of both disorders form a continuum extending into the general population, but it seems to be an oversimplification to typify psychiatric disorders such as autism and ADHD solely as extremes of brain structure abnormalities.