Journal of Autism and Developmental Disorders

, Volume 42, Issue 12, pp 2693–2701

Are Prenatal Ultrasound Scans Associated with the Autism Phenotype? Follow-up of a Randomised Controlled Trial

  • Yonit K. Stoch
  • Cori J. Williams
  • Joanna Granich
  • Anna M. Hunt
  • Lou I. Landau
  • John P. Newnham
  • Andrew J. O. Whitehouse
Original Paper

DOI: 10.1007/s10803-012-1526-8

Cite this article as:
Stoch, Y.K., Williams, C.J., Granich, J. et al. J Autism Dev Disord (2012) 42: 2693. doi:10.1007/s10803-012-1526-8

Abstract

An existing randomised controlled trial was used to investigate whether multiple ultrasound scans may be associated with the autism phenotype. From 2,834 single pregnancies, 1,415 were selected at random to receive ultrasound imaging and continuous wave Doppler flow studies at five points throughout pregnancy (Intensive) and 1,419 to receive a single imaging scan at 18 weeks (Regular), with further scans only as indicated on clinical grounds. There was no significant difference in the rate of Autism Spectrum Disorder between the Regular (9/1,125, 0.8 %) and Intensive (7/1,167, 0.6 %) groups, nor a difference between groups in the level of autistic-like traits in early adulthood. There is no clear link between the frequency and timing of prenatal ultrasound scans and the autism phenotype.

Keywords

Autism spectrum disorderAutismPrenatalUltrasonographyObstetricEnvironment

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Yonit K. Stoch
    • 1
  • Cori J. Williams
    • 1
  • Joanna Granich
    • 2
  • Anna M. Hunt
    • 2
  • Lou I. Landau
    • 3
  • John P. Newnham
    • 4
  • Andrew J. O. Whitehouse
    • 2
  1. 1.School of Psychology and Speech Pathology, Curtin Health Innovation Research InstituteCurtin UniversityPerthAustralia
  2. 2.Telethon Institute for Child Health Research, Centre for Child Health ResearchUniversity of Western AustraliaPerthAustralia
  3. 3.School of Paediatrics and Child HealthUniversity of Western AustraliaPerthAustralia
  4. 4.School of Women’s and Infants’ HealthUniversity of Western AustraliaPerthAustralia