Original Paper

Journal of Autism and Developmental Disorders

, Volume 42, Issue 11, pp 2323-2334

First online:

Parental Occupational Exposures and Autism Spectrum Disorder

  • Erin C. McCanliesAffiliated withNational Institute for Occupational Safety and Health, MS: L4050 Email author 
  • , Desta FekedulegnAffiliated withNational Institute for Occupational Safety and Health, MS: L4050
  • , Anna MnatsakanovaAffiliated withNational Institute for Occupational Safety and Health, MS: L4050
  • , Cecil M. BurchfielAffiliated withNational Institute for Occupational Safety and Health, MS: L4050
  • , Wayne T. SandersonAffiliated withCollege of Public Health, The University of Kentucky
  • , Luenda E. CharlesAffiliated withNational Institute for Occupational Safety and Health, MS: L4050
  • , Irva Hertz-PicciottoAffiliated withUniversity of California, Davis

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Abstract

Both self-report and industrial hygienist (IH) assessed parental occupational information were used in this pilot study in which 174 families (93 children with ASD and 81 unaffected children) enrolled in the Childhood Autism Risks from Genetics and Environment study participated. IH results indicated exposures to lacquer, varnish, and xylene occurred more often in the parents of children with ASD compared to the parents of unaffected children. Parents of children with ASD were more likely to report exposures to asphalt and solvents compared to parents of unaffected children. This study was limited by the small sample size, but results suggest that workplace exposures to some chemicals may be important in the etiology of ASD and deserve further investigation.

Keywords

Autism Autism spectrum disorder Parental exposures Parent Occupation Exposure