Original paper

Journal of Autism and Developmental Disorders

, Volume 41, Issue 10, pp 1342-1351

First online:

Modified Checklist for Autism in Toddlers: Cross-Cultural Adaptation and Validation in Spain

  • Ricardo Canal-BediaAffiliated withUniversity of Salamanca
  • , Patricia García-PrimoAffiliated withNational Research Institute of Rare Diseases, Instituto de Salud Carlos III Email author 
  • , María Victoria Martín-CillerosAffiliated withUniversity of Salamanca
  • , José Santos-BorbujoAffiliated withUniversity of Salamanca
  • , Zoila Guisuraga-FernándezAffiliated withUniversity of Salamanca
  • , Lorena Herráez-GarcíaAffiliated withUniversity of Salamanca
  • , María del Mar Herráez-GarcíaAffiliated withUniversity of Salamanca
  • , Leticia Boada-MuñozAffiliated withGregorio Marañón University Teaching Hospital
  • , Joaquín Fuentes-BiggiAffiliated withGuipúzcoa Polyclinic and the Guipuzka Autism Association (GAUTENA)
    • , Manuel Posada-de la PazAffiliated withNatinoal Research Institute of Rare Diseases, Instituto de Salud Carlos III and The Centre for Network Research on Rare Diseases (Centro de Investigación Biomédica en Red de Enfermedades Raras – CIBERER)

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Early detection and treatment have been shown to be effective in reducing disability severity caused by Autistic Spectrum Disorders (ASDs). As Spanish pediatricians have no detection tool, the Modified Checklist for Autism in Toddlers (M-CHAT) was first translated into and culturally adapted to Spanish. Validity and reliability studies were carried out in two different geographical areas of Spain, where M-CHAT was administered to two different samples, namely: 2,480 high- and low-risk children; and 2,055 low-risk children. The results obtained were similar to those yielded by the original M-CHAT studies. Differences were found in positive predictive value, due to the low ASD frequency observed in this study. M-CHAT is still being studied in a large population-based screening program in Spain.


Autism Screening Validation M-CHAT Psychometric values