An MRI Study of Minor Physical Anomalies in Autism
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The objective of this investigation was to examine the existence of minor physical anomalies (MPA) in autism. The interorbital and interlens distances were measured on MRI scans obtained from a sample of 40 non-mentally retarded individuals with autism and 41 healthy controls. No differences were observed between the two groups on any measurements. However, when the analysis was conducted using a split median procedure, individuals with autism and either low FSIQ, PIQ, or VIQ had shorter interorbital distances when compared to controls. Hypotelorism is a MPA that may be present in a subgroup of individuals with autism. Additional research is warranted using large sample sizes with a wide range of intellectual functioning.
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- An MRI Study of Minor Physical Anomalies in Autism
Journal of Autism and Developmental Disorders
Volume 36, Issue 5 , pp 607-611
- Cover Date
- Print ISSN
- Online ISSN
- Springer US
- Additional Links
- Physical anomalies
- Inter-orbit distance
- Industry Sectors
- Author Affiliations
- 1. Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O’Hara Street, Pittsburgh, PA, 15213, USA
- 2. Department of Psychiatry and Behavioral Sciences, Wayne State School of Medicine, Detroit, MI, USA