Article

Journal of Autism and Developmental Disorders

, Volume 36, Issue 3, pp 413-420

The Gluten-Free, Casein-Free Diet In Autism: Results of A Preliminary Double Blind Clinical Trial

  • Jennifer Harrison ElderAffiliated withCollege of Nursing, University of FloridaCollege of Nursing, University of Florida Email author 
  • , Meena ShankarAffiliated withGeneral Clinical Research Center, University of Florida
  • , Jonathan ShusterAffiliated withGeneral Clinical Research Center, University of Florida
  • , Douglas TheriaqueAffiliated withGeneral Clinical Research Center, University of Florida
  • , Sylvia BurnsAffiliated withCollege of Nursing, University of Florida
  • , Lindsay SherrillAffiliated withCollege of Nursing, University of Florida

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Abstract

This study tested the efficacy of a gluten-free and casein-free (GFCF) diet in treating autism using a randomized, double blind repeated measures crossover design. The sample included 15 children aged 2–16 years with autism spectrum disorder. Data on autistic symptoms and urinary peptide levels were collected in the subjects’ homes over the 12 weeks that they were on the diet. Group data indicated no statistically significant findings even though several parents reported improvement in their children. Although preliminary, this study demonstrates how a controlled clinical trial of the GFCF diet can be conducted, and suggests directions for future research.

Keywords

Autism diet gluten casein GFCF diet