International Ophthalmology

, Volume 34, Issue 3, pp 655–660

Chronic conjunctivitis due to Mycobacterium tuberculosis

  • Sunita Chaurasia
  • Muralidhar Ramappa
  • Somasheila I. Murthy
  • Geeta K. Vemuganti
  • Merle Fernandes
  • Savitri Sharma
  • Virender Sangwan
Case Report

DOI: 10.1007/s10792-013-9839-y

Cite this article as:
Chaurasia, S., Ramappa, M., Murthy, S.I. et al. Int Ophthalmol (2014) 34: 655. doi:10.1007/s10792-013-9839-y

Abstract

To report the clinical characteristics and treatment outcome in six patients with chronic conjunctivitis due to Mycobacterium tuberculosis. In this retrospective observational case series, all patients with a diagnosis of conjunctival tuberculosis seen in our clinics between January 2000 and January 2010 were reviewed. The clinical presentation, diagnostic investigations and response to medical therapy and outcomes were analyzed. Six patients (age range 15–47 years) were diagnosed with conjunctival tuberculosis. The mean duration from onset of symptoms to diagnosis was 6.5 months (range 1–12 months). Of the six patients, two had ulceration, one had a nodulo-ulcerative lesion, one had bilateral nodular epibulbar masses, and one had a hypertrophied papillary lesion. Systemic signs of tuberculosis were noted in two patients—pleural effusion in one and preauricular and submandibular lymph node involvement in the other. All patients had resolution of symptoms after treatment with four-drug anti-tuberculosis therapy (ATT). None had ocular or systemic recurrences after completion of ATT. Tuberculosis of the conjunctiva can have varied clinical presentation. Although a rare entity, it should be suspected in non-responding chronic conjunctivitis. A high index of suspicion and clinical examination aided by appropriate microbiological and histopathological testing can help in early diagnosis and management.

Keywords

Chronic conjunctivitisConjunctival tuberculosisMycobacterium tuberculosis

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Sunita Chaurasia
    • 1
  • Muralidhar Ramappa
    • 1
  • Somasheila I. Murthy
    • 1
  • Geeta K. Vemuganti
    • 2
  • Merle Fernandes
    • 3
  • Savitri Sharma
    • 4
  • Virender Sangwan
    • 1
  1. 1.Cornea and Anterior Segment ServicesL.V. Prasad Eye InstituteHyderabadIndia
  2. 2.Ophthalmic Pathology ServicesL.V. Prasad Eye InstituteHyderabadIndia
  3. 3.Cornea and Anterior Segment ServicesL.V. Prasad Eye InstituteVishakapatnamIndia
  4. 4.Jhaveri Microbiology CenterL.V. Prasad Eye InstituteHyderabadIndia