Analgesic and anti-inflammatory activities of 18-acetoxy-ent-kaur-16-ene from Annona squamosa L. bark
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- Chavan, M.J., Wakte, P.S. & Shinde, D.B. Inflammopharmacol (2011) 19: 111. doi:10.1007/s10787-010-0061-5
The Annona squamosa L. bark was collected from Ahmednagar district, India. 18-Acetoxy-ent-kaur-16-ene was isolated from petroleum ether extract (PE) and studied for its analgesic and anti-inflammatory activities. 18-Acetoxy-ent-kaur-16-ene at the doses of 12.5 and 25 mg/kg, and PE at a dose of 50 mg/kg exhibited significant analgesic along with anti-inflammatory activity.