Heart Failure Reviews

, Volume 15, Issue 4, pp 305–317

Perspective on the clinical application of troponin in heart failure and states of cardiac injury


  • Almasa Bass
    • School of PharmacyUNC Heart Failure Program
  • J. Herbert Patterson
    • School of PharmacyUNC Heart Failure Program
    • Department of Medicine and RadiologyUNC Heart Failure Program

DOI: 10.1007/s10741-008-9124-8

Cite this article as:
Bass, A., Patterson, J.H. & Adams, K.F. Heart Fail Rev (2010) 15: 305. doi:10.1007/s10741-008-9124-8


The ability to measure the appearance of cardiac specific forms of troponin in the blood represents a major advance in the clinical assessment of patients with many types of cardiovascular disease, especially acute coronary syndromes. In this review we focus on the utility of troponin in heart failure where this biomarker has emerged as an independent predictor of prognosis providing information beyond clinical assessment and measurement of b-type natriuretic peptides. The novel clinical role of troponin in a variety of states associated with myocardial injury, including chemotherapy and patients with cardiovascular risk factors, is discussed.


TroponinBiomarkerHeart failurePrognosis

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© Springer Science+Business Media, LLC 2009