Heart Failure Reviews

, Volume 13, Issue 1, pp 99-106

First online:

Medication adherence in heart failure

  • Paul J. HauptmanAffiliated withDivision of Cardiology, Saint Louis University School of Medicine Email author 

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Non-adherence with medical regimens in heart failure is a significant challenge and serves as a major reason that favorable outcomes associated with various therapies evaluated in clinical trials have not translated to the so-called real-world setting. Non-adherence has complex influences and is clearly associated with poorer outcomes. The approaches that are used or have been proposed to improve drug-taking behavior, such as in-hospital initiation of therapy, simplification of dosing regimens through adoption of combination and long-acting formulations, and improvements in provider–patient communication, are reviewed.


Heart failure Medication compliance Adherence