Medication adherence in heart failure
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- Hauptman, P.J. Heart Fail Rev (2008) 13: 99. doi:10.1007/s10741-007-9020-7
Non-adherence with medical regimens in heart failure is a significant challenge and serves as a major reason that favorable outcomes associated with various therapies evaluated in clinical trials have not translated to the so-called real-world setting. Non-adherence has complex influences and is clearly associated with poorer outcomes. The approaches that are used or have been proposed to improve drug-taking behavior, such as in-hospital initiation of therapy, simplification of dosing regimens through adoption of combination and long-acting formulations, and improvements in provider–patient communication, are reviewed.