Immunolocalisation of bilitranslocase in mucosecretory and parietal cells of the rat gastric mucosa
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- Nicolin, V., Grill, V., Micali, F. et al. J Mol Hist (2005) 36: 45. doi:10.1007/s10735-004-2920-0
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SummaryBilitranslocase is a plasma membrane carrier localised at the vascular pole of the rat liver cell, where it mediates uptake of organic anions from the blood into the liver. This carrier is also present in the epithelium of the rat gastric mucosa, with similar molecular mass and functional properties. An immunohistochemical study reveals that both the mucus-secreting cells of the gastric pit and the H+-secreting parietal cells express bilitranslocase. These data point to a possible role of bilitranslocase and of its food-borne substrates (anthocyanins and nicotinic acid) in regulating the function and the permeability of the gastric mucosa.
phosphate buffered saline solution
normal goat serum