Genetica

, Volume 126, Issue 1, pp 251–260

Y Chromosome Diversity in Brazilians: Switching Perspectives from Slow to Fast Evolving Markers

  • Denise R. Carvalho-Silva
  • Eduardo Tarazona-Santos
  • Jorge Rocha
  • Sérgio D. J. Pena
  • Fabrício R. Santos
Article

DOI: 10.1007/s10709-005-1454-z

Cite this article as:
Carvalho-Silva, D.R., Tarazona-Santos, E., Rocha, J. et al. Genetica (2006) 126: 251. doi:10.1007/s10709-005-1454-z

Abstract

We have previously shown that the Y chromosomes of ‘white’ Brazilians have their immediate geographical origin in Europe, with low frequency of sub-Saharan African chromosomes and virtual absence of Amerindian contribution. The typing of slow evolving polymorphisms on the Y chromosome also revealed no differences between Brazilians and Portuguese, the bulk of European immigrants to Brazil, and even among Brazilians from distinct regions of Brazil, the latter being in sharp contrast with mtDNA data. In order to test if the lack of differentiation is a sex-biased and not a marker-biased phenomenon, we decided to study faster evolving Y chromosome markers in samples from Brazil and Portugal previously studied. The population structure revealed by this work confirmed that there were indeed no significant differences between Brazil and Portugal and no population differentiation within the four geographical regions of Brazil, suggesting that this phenomenon is unrelated to the nature of the markers typed. Nevertheless the fast evolving markers did uncover a higher within population diversity in Brazil than Portugal, which could be explained by the input of diverse European Y chromosomes carried by several migration waves to Brazil. Our present data highlight the significance of typing and combining Y markers that evolve according to distinct mutational paces to usefully assess the levels of diversity in a given population, and can be applied in the study of populations derived from distinct geographical origins such as the Brazilians.

Keywords

αh heteroduplex systemBraziliansdifferentiationmicrosatellitesunique event polymorphismsY chromosome

Abbreviations

AMOVA

analysis of molecular variance

ANOVA

analysis of variance

CI

Confidence Interval

DNA

deoxyribonucleic acid

UEPs

unique event polymorphisms

Y-μsat

Y microsatellites

Copyright information

© Springer 2006

Authors and Affiliations

  • Denise R. Carvalho-Silva
    • 1
  • Eduardo Tarazona-Santos
    • 1
    • 2
  • Jorge Rocha
    • 3
  • Sérgio D. J. Pena
    • 1
  • Fabrício R. Santos
    • 2
  1. 1.Departamento de Bioquímica e ImunologiaUniversidade Federal de Minas GeraisBelo HorizonteBrazil
  2. 2.Departamento de Biologia GeralUniversidade Federal de Minas GeraisBelo HorizonteBrazil
  3. 3.Instituto de Patologia e Imunologia Molecular da Universidade do PortoPortoPortugal