Familial Cancer

, Volume 11, Issue 2, pp 269–278

French women’s breast self-examination practices with time after undergoing BRCA1/2 genetic testing

  • C. Maheu
  • T. Apostolidis
  • A. Petri-Cal
  • E. Mouret-Fourme
  • M. Gauthier-Villars
  • C. Lasset
  • P. Berthet
  • J.-P. Fricker
  • O. Caron
  • E. Luporsi
  • L. Gladieff
  • C. Noguès
  • C. Julian-Reynier
Original Article

DOI: 10.1007/s10689-012-9512-z

Cite this article as:
Maheu, C., Apostolidis, T., Petri-Cal, A. et al. Familial Cancer (2012) 11: 269. doi:10.1007/s10689-012-9512-z

Abstract

To assess the impact of BRCA1/2 genetic test results on cancer-free women’s breast-self-examination (BSE) practices and to prospectively determine their influence on psychological functioning. A prospective longitudinal study on French women’s BSE practices and frequencies in BRCA1/2 carriers (N = 217) and non-carriers (N = 313) 1 and 2 years following disclosure of the test results, along with psychological factors predicting BSE practices. Before disclosure, BSE was practised by 47.2% of the women, and increased to 57.3% 1 year later. No change in the women’s practices was noted between 12 and 24 months after the test. Carriers and non-carriers practicing regularly BSE at baseline were, respectively 8 to 6 times more likely to be practising BSE regularly at 12 months after being tested. Among the carriers, having fewer depressive symptoms at baseline and believing in the ability of BSE to detect breast cancer were found to be the most decisive factors associated with BSE practices 1 year after disclosure, following adjustment for BSE baseline practices. Among the non-carriers, believing in the ability of BSE to detect breast cancer, greater post-test anxiety, and a higher perceived risk of breast cancer were found to be predictors of post-test BSE practices after adjusting for BSE baseline practices. In France, where performing BSE is neither mandatory nor recommended, an increase in BSE practices was found to occur after disclosure of women’s genetic test results, regardless of their carrier status.

Keywords

Breast self-examination practicesPsychological factorsBRCA1/2 familiesFrance

Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • C. Maheu
    • 1
    • 2
    • 3
    • 4
  • T. Apostolidis
    • 1
    • 2
    • 3
    • 5
  • A. Petri-Cal
    • 1
    • 2
    • 3
  • E. Mouret-Fourme
    • 6
    • 7
  • M. Gauthier-Villars
    • 7
  • C. Lasset
    • 8
    • 9
  • P. Berthet
    • 10
  • J.-P. Fricker
    • 11
  • O. Caron
    • 12
  • E. Luporsi
    • 13
  • L. Gladieff
    • 14
  • C. Noguès
    • 6
    • 7
  • C. Julian-Reynier
    • 1
    • 2
    • 3
    • 15
  1. 1.INSERM, UMR912MarseilleFrance
  2. 2.Aix-Marseille Université, UMR912MarseilleFrance
  3. 3.IRD, UMR912MarseilleFrance
  4. 4.York UniversityTorontoCanada
  5. 5.Laboratoire de Psychologie SocialeAix-Marseille UniversitéAix-en-ProvenceFrance
  6. 6.Centre René HugueninSaint CloudFrance
  7. 7.Institut CurieParisFrance
  8. 8.Centre Léon BérardLyonFrance
  9. 9.Université Lyon1, UMR CNRS 5558VilleurbanneFrance
  10. 10.Centre François BaclesseCaenFrance
  11. 11.Centre Paul StraussStrasbourgFrance
  12. 12.Institut Gustave RoussyParisFrance
  13. 13.Centre Alexis VautrinNancyFrance
  14. 14.Institut Claudius RegaudToulouseFrance
  15. 15.Institut Paoli-Calmettes, UMR912Marseille cedex 09France