Original Paper

Familial Cancer

, Volume 5, Issue 4, pp 405-409

First online:

Awareness of gynecologic surveillance in women from hereditary non-polyposis colorectal cancer families

  • Kathleen YangAffiliated withDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF Comprehensive Cancer Center
  • , Brian AllenAffiliated withColorectal Cancer Prevention Program, Cancer Risk Program, UCSF Comprehensive Cancer Center
  • , Peggy ConradAffiliated withColorectal Cancer Prevention Program, Cancer Risk Program, UCSF Comprehensive Cancer Center
  • , C. Bethan PowellAffiliated withDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF Comprehensive Cancer Center
  • , Jonathan TerdimanAffiliated withColorectal Cancer Prevention Program, Cancer Risk Program, UCSF Comprehensive Cancer Center
  • , Lee-may ChenAffiliated withDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF Comprehensive Cancer Center Email author 

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Objective

To determine knowledge of gynecologic cancer risk and screening in women with HNPCC.

Study design

Forty-three women with HNPCC were counseled through a gastrointestinal cancer risk program, and later sent a questionnaire regarding their screening practices for gynecologic neoplasms.

Results

Twenty-seven (63%) of 43 responded. Fifteen (55%) of 27 had previously been diagnosed with cancer. Among 16 women with a uterus, 11 (69%) reported surveillance by ultrasound or endometrial sampling. Among 21 respondents with ovaries, 13 (62%) reported screening by ultrasound or CA125. Twenty-two (81%) of 27 had seen a gynecologist after receiving their HNPCC diagnosis, but only 12% recalled hearing about risks from their gynecologist, and␣8% from their gynecologic oncologist. Genetic counselors were cited as the most common source (48%) of gynecologic cancer risk information.

Conclusions

While the effectiveness of surveillance remains in question, gynecologists can be a source of information regarding gynecologic cancer risk for women from HNPCC families.

Keywords

Endometrial cancer Hereditary non-polyposis colorectal cancer Ovarian cancer Surveillance