Familial Cancer

, Volume 4, Issue 2, pp 139–143

An unusual case of Turcot’s syndrome associated with ileal adenocarcinoma, intestinal non-Hodgkin’s lymphoma, and duodenal adenocarcinoma. Review of the classification and genetic basis of Turcot’s syndrome

Article

DOI: 10.1007/s10689-004-2759-2

Cite this article as:
Murphy, H.R., Taylor, W., Ellis, A. et al. Familial Cancer (2005) 4: 139. doi:10.1007/s10689-004-2759-2

Abstract

A 38-year-old man with a history of colonic and small bowel polyposis and glioblastoma was investigated for dyspepsia. Upper GI endoscopy identified an abnormal area in the duodenum, confirmed by histology as high grade non-Hodgkin’s B cell MALT lymphoma. Although cases of Turcot’s syndrome (TS) (colonic polyposis and primary brain tumour occuring in the same patient) have been previously described, association with haematological malignancy is rare. This is the first report of intestinal lymphoma occurring in an adult with TS.

Keywords

colon cancer duodenal cancer family history glioblastoma non-Hodgkin’s lymphoma polyposis Turcot’s syndrome 

Copyright information

© Springer 2005

Authors and Affiliations

  • H. R. Murphy
    • 1
  • W. Taylor
    • 2
  • A. Ellis
    • 1
    • 3
  • R. Sturgess
    • 4
  1. 1.Department of Clinical GeneticsRoyal Liverpool Children’s Hospital – Alder HeyLiverpoolUK
  2. 2.Department of PathologyUniversity Hospital AintreeLiverpoolUK
  3. 3.Department of GastroenterologyRoyal Liverpool University HospitalLiverpoolUK
  4. 4.Department of GastroenterologyUniversity Hospital AintreeLiverpoolUK

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