Summary
This study focuses on an origin of interaction mechanism of microwave radiation with nervous system—quasi-thermal field effect. The microwave field can cause fluctuations and vibration of the charged particles and membranes in tissues. The hypothesis is, that this phenomenon is similar to the effect caused by Brown motion initiated by temperature and results in the same effects without rise in temperature. The electric field of 1 V/cm can introduce disturbance of the thermal equilibrium inside a cell of 10 μm radius, which is equivalent to disturbance produced by temperature rise of 1 K. The hypothesis, that microwave heating should cause an effect independent of the microwave modulation frequency, while field effect depends on modulation frequency, was examined experimentally. The 450 MHz microwave radiation, modulated at 7, 14 and 21 Hz frequencies, power density at the skin 0.16 mW/cm2, was applied. The experimental protocol consisted of two series of five cycles of the repetitive microwave exposure at fixed modulation frequencies. Relative changes in EEG theta, alpha and beta rhythms of the group of 13 healthy volunteers were analysed. Analysis of the experimental data shows that: (1) statistically significant changes in EEG rhythms depend on modulation frequency of the microwave field; (2) microwave stimulation causes an increase of the EEG energy level; (3) the effect is most intense at beta1 rhythm and higher modulation frequencies. These findings confirm the quasi-thermal origin of the effect, different from average heating.
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References
Adair, E.R., Cobb, B.L., Mylacraine, K.S. and Kelleber, S.A.: 1999, “Human Exposure to Two Radio Frequencies (450 and 2450 MHz) Similarities and Differences in Physiological Response,” Bioelectromagnetics 20(S4), 12–20.
Adair, E.R., Mylacraine, K.S. and Cobb, B.L.: 2001, “Partial Body Exposure of Human Volunteers to 2450 MHz Pulsed or CW Field Provokes Similar Thermoregulatory Responses,” Bioelectromagnetics 22, 246–259.
Adair, R.K.: 2002, “Vibrational Resonances in Biological Systems at Microwave Frequencies,” Biophysical Journal 82, 1147–1152.
Balzano, Q. and Sheppard, A.: 2003, “RF Nonlinear Interaction in Living Cells-I: Nonequilibrium Thermodynamic Theory,” Bioelectromagnetics 24, 473–482.
Baranski, S.Z. and Edelwejn, Z.: 1975, “Experimental Morphologic and Electroentcephalographic Studies of Microwave Effects on the Nervous System,” Annals of the New York Academy of Sciences 247, 109–117.
Bawin, S.M., Gavalas-Medici, R.J. and Adey, W.R.: 1973, “Effects of Modulated Very High Frequency Fields on Specific Brain Rhythms in Cats,” Brain Research 58, 365–384.
Blank, M. and Goodman, R.: 1999, “Electromagnetic Fields may Act Directly on DNA,” J.Cel. Biochem. 15, 369–374.
Borbely, A.A., Huber, R., Graf, T., Fuchs, B., Gallmann, E. and Achermann, P.: 1999, “Pulsed High-Frequency Electromagnetic Field Affects Human Sleep and Sleep Electroencephalogram,” Neuroscience Letters 275, 207–210.
Chizhenkova, R.A.: 1988, “Slow Potentials and Spike Unit Activity of the Cerebral Cortex of Rabbits Exposed to Microwaves,” Bioelectromagnetics 9, 337–345.
Chua, E., Gose, E., Vinas, F.C., Dujovny, M. and Star, J.: 1999, “Temperature Distribution Produced in Brain Tissue and Other Media by a Radiofrequency Hyperthermia Generator,” Stereotactic and Functional Neurosurgery 72, 22–34(DOI: 10.1159/000029669)
De Lorge, J.O. and Ezell, C.S.: 1980, “Observing Responses of Rats Exposed to 1.28 and 5.62 GHz Microwaves,” Bioelectromagnetics 1, 183–198.
Foster, K.R., Lozano-Nieto, A., Riu, P.J. and Ely, T.S.: 1998, “Heating of Tissues by Microwaves: A Model Analysis,” Bioelectromagnetics 19(7), 420–428.
Foster, K.R. and Schwan, H.P.: 1996, “Dielectric Properties of Tissues, in Handbook of Biological Effects of Electromagnetic Fields,” in C. Polk and E. Postow (eds.), CRC Press, Boca Raton, New York, London, Tokio, pp. 25–102.
Gajšek, P., Hurt, W.D., Ziriax, J.M. and Mason, P.A.: 2001, “Parametric Dependence of SAR on Permittivity Values in a Man Model,” IEEE Trans.Biomed. Eng. 48, 1169–1177.
Galarreta, M. and Hestrin, S.: 1999, “A Network of Fast-Spiking Cells in the Neocortex Connected by Electrical Synapses,” Nature 412, 72–75.
Gavalas-Medici, R.J. and Day-Magdaleno, S.R.: 1976, “Extremely Low Frequency, Weak Electric Fields Affect Schedule-Controlled Behaviour of Monkeys,” Nature 261, 256–270.
Goodman, R. and Blank, M.: 2002, “Insights into Electromagnetic Interaction Mechanisms,” J Cell Physiol 192, 16–22.
Hinrikus, H., Parts, M., Lass, J. and Tuulik, V.: 2004, “Changes in Human EEG Caused by Low-Level Modulated Microwave Stimulation,” Bioelectromagnetics, 25, 431–440.
Huber, R., Graf, T., Cote, K.A., Wittmann, L., Gallmann, E., Matter, D., Schuderer, J., Kuster, N., Borbely, A.A. and Achermann, P.: 2000, “Exposure to Pulsed High-Frequency Electromagnetic Field During Waking Affects Human Sleep EEG,” Neuroreport 11, 3321–3325.
Hurt, D.H., Ziriax, J.M. and Mason, P.A.: 2000, “Variability in EMF Permittivity Values: Implications for SAR Calculations,” IEEE Trans.Biome. Eng. 47, 396–401.
IEEE Standards for safety levels with respect to human exposure to radio frequency electromagnetic fields, 3 to 300 GHz. ANSI/IEEE C95.1-1999 Edition. Institute of Electrical and Electronic Engineers, Piscataway, NJ, 1999.
Johnson, C. and Guy, A.W.: 1972, “Non-Ionizing Electromagnetic Rhythm Effects in Biological Materials and System,” Proceedings of the IEEE 60, 692–701.
Kholodov, Y.A.: 1966, The Effect of Electromagnetic and Magnetic Fields on the Central Nervous System, Nauka Press, Moscow.
Kholodov, Y.A.: 1967, Effects of Electromagnetic and Magnetic Fields on the Central Nervous System, (NASA-NASATT, F-465) Washington, DC.
King, R.W.P. and Smith, G.S., Antennas in matter: fundamentals, theory and application, MIT Press, Cambridge, MA.
Lass, J., Tuulik, V., Ferenets, R., Riisalo, R. and Hinrikus, H.: 2002, “Effects of 7 Hz-Modulated 450 MHz Electromagnetic Radiation on Human Performance in Visual Memory Tasks,” Int. J. Radiat. Biol. 78, 937–944.
Leszczynski, D., Joenvääea, S., Reivinen, J. and Kuokka, R.: 2002, “Non-Thermal Activation of the hsp27/p38MAPK Stress Pathway by Mobile Phone Radiation in Human Endothelial Cells: Molecular Mechanism for Cancer- and Blood-Brain Barrier-Related Effects,” Differentiation 70, 120–129.
Liu, J., Zhou, Y.X. and Deng, Z.S.: 2002, “Sinusoidal Heating Method to Noninvasively Measure Tissue Perfusion,” IEEE Trans Biomed Eng. 49(8), 867–877.
Lutty, G., Mcleod, D. and Johnson, M.: 2000, “Effects of High Power Microwaves on the Retina of the Rhesus Monkey,” Bioelectromagnetics 21, 439–454.
Malmivuo, J. and Plonsey, R.: 1993, Bioelectromagnetism, Oxford University Press, New York.
Mann, K. and Roschke, J.: 1996, 'Effects of Pulsed High-Frequency Electromagnetic Fields on Human Sleep,” Neuropsychobiology 33, 41–47.
Mitchell, C.L., Switzer, W.G. and Bronough, E.L.: 1977, “Hyperactivity and Disruption of Operant Behavior in Rats After Multiple Exposures to Microwave Exposure, Radio Sci, 12(6S), 263–271.
Persson, B., Salford, L. and Brun, A.: 1997, “Blood-Brain Barrier Permeability in Rats Exposed to Electromagnetic Fields Used in Wireless Communicarion,” Wireless Networks, 3, 455–461.
Reiser, H., Dimpfel, W. and Schober, F.: 1995, “The Influence of Electromagnetic Fields on Human Brain Activity,” European Journal of Medical Research 1, 27–32.
Salford, l., Brun, A., Eberhardt, J., Malmgren, L. and Persson, B.: 2003, “Nerve Cell Damage in Mammalian Brain After Exposure to Microwaves From GSM Mobile Phones,” Environmental Health Perspectives, 111(7), 881–883.
Saunders, R.D., Kowalczuk, C.I., Sienkiewicz, Z.J.: 1991, “Biological Effects of Exposure to Non-Ionising Electromagnetic Fields and Radiations: III. Radiofrequency and Microwave Radiation”. Oxon. UK: National Radiological Protection Board, Report No NRPB-R240.
Schirmacher, A., Winters, S., Fisher, S., Goeke, J., Galla, H.J., Kullnick, I., Ringelstein, E.B. and Stogbauer, F.: 2000, “Electromagnetic Fields (1.8 GHz) Increase the Permeability to Sucrose of the Blood-Brain Barrier in Vitro,” Bioelectromagnetics 21, 338–345.
Vorobyov, V.V., Galchenko, A.A., Kukushkin, N.I. and Akoev, I.G.: 1997, “Effects of Weak Microwave Fields Amplitude Modulated at ELF on EEG of Symmetric Brain Areas in Rats,” Bioelectromagnetics 18, 293–298.
Wagner, P., Roschke, J., Mann, K., Hiller, W. and Frank, C.: 1998, “Human Sleep Under the Influence of Pulsed Radiofrequency Electromagnetic Fields: A Polysomnographic Study Using Standardized Conditions,” Bioelectromagnetics 19, 199–202.
Yablonskiy, D.A., Ackerman, J.H. and Raichle, M.E.: 2000, “Coupling Between Changes in Human Brain Temperature and Oxidative Metabolism During Prolonged Visual Stimulation,” Neurobiology 97(13), 7603–7608.
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Hinrikus, H., Bachmann, M., Tomson, R. et al. Non-Thermal Effect of Microwave Radiation on Human Brain. Environmentalist 25, 187–194 (2005). https://doi.org/10.1007/s10669-005-4282-x
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DOI: https://doi.org/10.1007/s10669-005-4282-x