European Journal of Epidemiology

, 21:323

Import of West Nile Virus Infection in the Czech Republic


  • Zdenek Hubálek
    • Medical Zoology Laboratory, Institute of Vertebrate BiologyAcademy of Sciences
  • Lubomíra Lukáčová
    • Internal DepartmentUniversity Hospital
  • Jiří Halouzka
    • Medical Zoology Laboratory, Institute of Vertebrate BiologyAcademy of Sciences
  • Petr Širůček
    • Internal DepartmentUniversity Hospital
  • Jiří Januška
    • Virology DepartmentRegional Institute of Public Health
  • Jarmila Přecechtělová
    • Neurology DepartmentDistrict Hospital
  • Petr Procházka
    • Neurology DepartmentDistrict Hospital

DOI: 10.1007/s10654-006-0019-5

Cite this article as:
Hubálek, Z., Lukáčová, L., Halouzka, J. et al. Eur J Epidemiol (2006) 21: 323. doi:10.1007/s10654-006-0019-5


We report West Nile virus infection of the central nervous system in a 69-year-old man, residing in North Moravia (Czech Republic), who visited the USA from 6 July to 31 August 2002. He developed fever with fatigue at the end of his US stay, and was hospitalized in Ostrava after his return on 3 September with fever (up to 39.5 °C), fatigue, anorexia, moderate laryngotracheitis, dizziness, insomnia, blurred speech, and a marked bradypsychism. EEG demonstrated a slow bifrontal theta–delta activity, and CT of the brain a slight hydrocephalus. A significant increase of antibodies neutralizing West Nile virus was detected between the first (1:16) and second (1:256) blood serum sample. The patient recovered gradually and was released from hospital on 16 September. This is the first recorded human case of West Nile fever (WNF) imported to the Czech Republic. Nine similar cases of WNF import from the USA have already been reported in other European countries – France, Denmark, the Netherlands, and Germany.


CNS infectionFlavivirusImportWest Nile virus

Copyright information

© Springer 2006