Ecotoxicology

, Volume 18, Issue 1, pp 87–93

Geostatistical analysis of biomarkers of genotoxicity in cattle, Bos taurus and Bos taurus × Bos indicus, sentinels near industrial facilities

  • Wesley BissettJr.
  • Roger Smith
  • L. Garry Adams
  • Robert Field
  • William Moyer
  • Tim Phillips
  • H. Morgan Scott
  • James A. Thompson
Article

DOI: 10.1007/s10646-008-0261-6

Cite this article as:
Bissett, W., Smith, R., Adams, L.G. et al. Ecotoxicology (2009) 18: 87. doi:10.1007/s10646-008-0261-6

Abstract

This study, performed at the behest of ranchers living and working down-prevailing wind from industrial facilities located in Calhoun County, Texas investigated locational risks to ecosystem health associated with proximity to specific industrial complexes. Concerns expressed were for potential genotoxicity in cattle resulting from the release of complex chemical mixtures. The Comet Assay and flow cytometric evaluation of variations in DNA content were utilized to evaluate DNA damage. Bayesian geo-statistical analysis revealed the presence of important spatial processes. The Comet assay’s optical density provided a strong indication of increased damage down-prevailing wind from the industrial complexes. Results indicated that proximity to and location down-prevailing winds from industrial facilities increased the locational risk of genotoxicity in this sentinel species.

Keywords

Chromosomal alterationsDNA–protein cross-linkageSpatially oriented genotoxic response

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Wesley BissettJr.
    • 1
  • Roger Smith
    • 2
  • L. Garry Adams
    • 2
  • Robert Field
    • 1
  • William Moyer
    • 1
  • Tim Phillips
    • 3
  • H. Morgan Scott
    • 3
  • James A. Thompson
    • 1
  1. 1.Department of Large Animal Clinical SciencesTexas A&M UniversityCollege StationUSA
  2. 2.Department of Veterinary PathobiologyTexas A&M UniversityCollege StationUSA
  3. 3.Department of Veterinary Integrative BiosciencesTexas A&M UniversityCollege StationUSA