Original Research Article

Documenta Ophthalmologica

, Volume 118, Issue 3, pp 205-216

First online:

Rod and S-cone driven ERG signals at high retinal illuminances

  • Jan KremersAffiliated withDepartment of Ophthalmology, University Hospital Erlangen-NurembergDepartment of Experimental Ophthalmology, University Eye HospitalSchool of Life Sciences, University of Bradford Email author 
  • , Dariusz CzopAffiliated withDepartment of Experimental Ophthalmology, University Eye HospitalTadeusz Krwawicz Chair of Ophthalmology, Medical University of Lublin
  • , Barbara LinkAffiliated withDepartment of Ophthalmology, University Hospital Erlangen-Nuremberg

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Abstract

The purpose of the present study was to investigate whether L- and M-cone driven responses can be influenced by concomitant modulation in the rods or the S-cones. In addition, it was studied whether a change in the state of adaptation in L- or M-cones can have a different influence on ERG data when simultaneously the mean number of photoisomerizations in either rods or S-cones is altered. It was found that rods and/or S-cones cannot be neglected when measuring L- or M-cone driven ERGs.

Keywords

Electroretinogram Rod driven signals S-cone driven signals Temporal frequency Retinal illuminance