Original Research Article

Documenta Ophthalmologica

, Volume 114, Issue 3, pp 111-116

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

ISCEV standard for clinical pattern electroretinography—2007 update

  • Graham E. HolderAffiliated withMoorfields Eye Hospital Email author 
  • , Mitchell G. BrigellAffiliated withPfizer Global R&D
  • , Marko HawlinaAffiliated withUniversity Eye Hospital, Medical Centre Ljubljana
  • , Thomas MeigenAffiliated withDepartment of Ophthalmology, University of Würzburg
  • , VaeganAffiliated withUniversity of New South Wales
  • , Michael BachAffiliated withUniversity Eye Clinic
  • , for the International Society for Clinical Electrophysiology of Vision


The pattern electroretinogram (PERG) is a retinal response evoked by viewing a temporally alternating pattern, usually a black and white checkerboard or grating. The PERG is important in clinical and research applications because it provides information both about retinal ganglion cell function and, because the stimulus is customarily viewed with central fixation, the function of the macula. The PERG can therefore facilitate interpretation of an abnormal pattern VEP by revealing the retinal responses to a similar stimulus to that used for the VEP. However, practitioners may have difficulty choosing between the different techniques for recording the PERG that have been described in the literature. The International Society for Clinical Electrophysiology of Vision published a standard for clinical PERG recording in 2000 to assist practitioners in obtaining good quality reliable responses and to facilitate inter-laboratory communication and comparison. This document is the scheduled revision of that standard.


Clinical electrophysiology Electroretinogram Pattern electroretinogram Retina Macula