Digestive Diseases and Sciences

, Volume 57, Issue 1, pp 4–8

Abdominal Bloating and Distension: What Is the Role of the Microbiota

Review

DOI: 10.1007/s10620-011-1834-4

Cite this article as:
Issa, B., Wafaei, N.A. & Whorwell, P.J. Dig Dis Sci (2012) 57: 4. doi:10.1007/s10620-011-1834-4

Abstract

Most patients with irritable bowel syndrome complain of a sensation of an increase in pressure within their abdomen during the course of the day which is called bloating and, in approximately half of these individuals, this symptom is accompanied by an actual increase in abdominal girth, which is referred to as distension. The pathophysiology of these two phenomena is somewhat different and it is now recognised that a whole variety of overlapping mechanisms are involved. Some of these are potentially amenable to treatment by modification of the bacterial flora of the gut and this article reviews the evidence for this.

Keywords

Irritable bowel syndrome Bloating Distension Microbiome 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Neurogastroenterology Unit, Department of Translational MedicineUniversity of ManchesterManchesterUK
  2. 2.Department of General and Colorectal SurgeryFairfield General Hospital, The Pennine Acute Hospitals NHS TrustBuryUK
  3. 3.Education and Research CentreWythenshawe HospitalManchesterUK

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