, Volume 55, Issue 7, pp 1811-1814
Date: 11 Jun 2010

Radiofrequency Ablation of Barrett’s Esophagus: Let’s Not Get Ahead of Ourselves

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Radiofrequency ablation (RFA) represents an exciting advance for the treatment of Barrett’s esophagus. The research work on RFA performed to date has involved a stepwise progression from initial animal studies to human studies prior to esophagectomy, human dosimetry studies, single-center studies, multicenter nonrandomized studies, and ultimately multicenter, randomized, controlled trials [15]. This process also led to modifications in the RFA technique and to the development of the focal ablation device. Regardless of the eventual role of RFA, this series of studies illustrates the appropriate steps in the development and application of future ablative technologies. However, this approach may be limited to certain subsets of patients by the high costs required for the development and widespread application of new endoscopic therapeutic technologies. Nevertheless, the impact of this development paradigm in the evolution of RFA is obvious, and both the investigators and the manufacture ...

An erratum to this article can be found at http://dx.doi.org/10.1007/s10620-010-1345-8