Erosive Esophagitis in Asymptomatic Subjects: Risk Factors
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Asymptomatic erosive esophagitis is a common yet rarely reported disease. The purpose of this study is to investigate the prevalence of asymptomatic erosive esophagitis and to identify the risk factors for this disease.
Materials and Methods
In this study, we investigated 572 asymptomatic subjects undergoing health check-ups after upper gastrointestinal endoscopy. The severity of esophagitis was evaluated by the Los Angeles classification, and the independent risk factors for asymptomatic esophagitis were analyzed by the logistic regression method.
The results showed the prevalence of erosive esophagitis in asymptomatic subjects was 12% (70/572). In all asymptomatic subjects, erosive esophagitis was grade A (71%) or B (29%). Univariate analysis revealed that male gender, high body mass index (BMI), and consumption of tobacco, alcohol, tea, spicy foods, and betel nut were associated with the development of erosive esophagitis. Multivariate analysis revealed that male gender (OR, 3.8, 95% CI, 1.5–9.3) and high BMI (BMI 25–30: OR, 2.3, 95% CI, 1.3–4.2; BMI >30: OR, 3.8, 95% CI, 1.3–10.9) were independent predictors of erosive esophagitis.
Our data revealed male gender and high BMI are independent risk factors for asymptomatic erosive esophagitis.
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- Erosive Esophagitis in Asymptomatic Subjects: Risk Factors
Digestive Diseases and Sciences
Volume 55, Issue 5 , pp 1320-1324
- Cover Date
- Print ISSN
- Online ISSN
- Springer US
- Additional Links
- Erosive esophagitis
- Health check-up
- Industry Sectors
- Author Affiliations
- 1. Department of Family Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
- 2. Department of Community Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
- 3. Faculty of Public Health, Kaohsiung Medical University, Kaohsiung, Taiwan
- 4. Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, 386 Ta-Chung 1 st Road, Kaohsiung, 80424, Taiwan