Digestive Diseases and Sciences

, Volume 55, Issue 5, pp 1320–1324

Erosive Esophagitis in Asymptomatic Subjects: Risk Factors

Authors

  • Fu-Wei Wang
    • Department of Family MedicineKaohsiung Veterans General Hospital
  • Ming-Shium Tu
    • Department of Family MedicineKaohsiung Veterans General Hospital
  • Hung-Yi Chuang
    • Department of Community MedicineKaohsiung Medical University Hospital
    • Faculty of Public HealthKaohsiung Medical University
  • Hsien-Chung Yu
    • Division of Gastroenterology, Department of Internal MedicineKaohsiung Veterans General Hospital
  • Lung-Chih Cheng
    • Division of Gastroenterology, Department of Internal MedicineKaohsiung Veterans General Hospital
    • Division of Gastroenterology, Department of Internal MedicineKaohsiung Veterans General Hospital
Original Article

DOI: 10.1007/s10620-009-0888-z

Cite this article as:
Wang, F., Tu, M., Chuang, H. et al. Dig Dis Sci (2010) 55: 1320. doi:10.1007/s10620-009-0888-z

Abstract

Introduction

Asymptomatic erosive esophagitis is a common yet rarely reported disease. The purpose of this study is to investigate the prevalence of asymptomatic erosive esophagitis and to identify the risk factors for this disease.

Materials and Methods

In this study, we investigated 572 asymptomatic subjects undergoing health check-ups after upper gastrointestinal endoscopy. The severity of esophagitis was evaluated by the Los Angeles classification, and the independent risk factors for asymptomatic esophagitis were analyzed by the logistic regression method.

Results

The results showed the prevalence of erosive esophagitis in asymptomatic subjects was 12% (70/572). In all asymptomatic subjects, erosive esophagitis was grade A (71%) or B (29%). Univariate analysis revealed that male gender, high body mass index (BMI), and consumption of tobacco, alcohol, tea, spicy foods, and betel nut were associated with the development of erosive esophagitis. Multivariate analysis revealed that male gender (OR, 3.8, 95% CI, 1.5–9.3) and high BMI (BMI 25–30: OR, 2.3, 95% CI, 1.3–4.2; BMI >30: OR, 3.8, 95% CI, 1.3–10.9) were independent predictors of erosive esophagitis.

Conclusion

Our data revealed male gender and high BMI are independent risk factors for asymptomatic erosive esophagitis.

Keywords

Erosive esophagitisAsymptomaticEndoscopyHealth check-up

Copyright information

© Springer Science+Business Media, LLC 2009