Article

Digestive Diseases and Sciences

, 53:217

First online:

Pneumatosis Intestinalis and Portal Venous Gas Without Bowel Ischemia in a Patient Treated with Irinotecan and Cisplatin

  • David KungAffiliated withBrigham and Women’s Hospital, Harvard Medical School
  • , Daniel T RuanAffiliated withBrigham and Women’s Hospital, Harvard Medical School Email author 
  • , Rodney K. ChanAffiliated withBrigham and Women’s Hospital, Harvard Medical School
  • , Melissa L. EricssonAffiliated withWestern Connecticut State University
  • , Mandeep S. SaundAffiliated withBrigham and Women’s Hospital, Harvard Medical School

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Abstract

Pneumatosis intestinalis and gas within the portal venous system are findings predictive of bowel ischemia. The etiologies of these alarming radiographic signs are diverse and not all causes require emergent surgical intervention. The combination of pneumatosis intestinalis, portal venous gas, and acidosis typically portends bowel ischemia and inevitable necrosis. This case report is the first description of benign pneumatosis and portal venous gas secondary to irinotecan and cisplatin.

Keywords

Pneumatosis intestinalis Portal venous gas Irinotecan