Digestive Diseases and Sciences

, Volume 51, Issue 5, pp 858–863

Presenting Symptoms of Nonerosive and Erosive Esophagitis in Pediatric Patients


    • Riley Hospital for Children
  • Eric Hassall
    • British Columbia Children's HospitalUniversity of British Columbia
  • Yi-Lin Chiu
    • Abbott Laboratories
  • Fouad Amer
    • TAP Pharmaceutical Products Inc.
  • Melvin B. Heyman
    • UCSF Children's HospitalUniversity of California, San Francisco
Original Paper

DOI: 10.1007/s10620-006-9095-3

Cite this article as:
Gupta, S.K., Hassall, E., Chiu, Y. et al. Dig Dis Sci (2006) 51: 858. doi:10.1007/s10620-006-9095-3


Children and adolescents with symptomatic gastroesophageal reflux disease (GERD) and erosive esophagitis (EE) of grade ≥2 (n=45) or nonerosive esophagitis (NEE) (n=45) were assessed to determine the relationship between presenting symptoms, esophagitis severity, and patient age. Overall, regurgitation/vomiting, abdominal pain, and cough were the most frequent symptoms. The prevalence and severity of anorexia/feed refusal was significantly greater in EE versus NEE children; this symptom was also significantly more prevalent in younger (1–5 years) children (both NEE and EE groups) compared to older children. Cough was significantly less severe in NEE adolescents than in younger children. Cough, anorexia/feed refusal, and regurgitation/vomiting were more severe and heartburn was less severe in EE children aged 1–5 years compared with older patients. In conclusion, GERD in children manifests differently than that in adults and symptoms vary with patient age. Symptoms were not predictive of presence or lack of mucosal damage.


ChildrenAdolescentsGastroesophageal reflux diseaseNonerosive reflux diseaseErosive esophagitisFeeding problemsCoughAbdominal pain

Copyright information

© Springer Science+Business Media, Inc. 2006