Article

Digestive Diseases and Sciences

, Volume 51, Issue 5, pp 1012-1015

Celiac Disease in African-Americans

  • Pardeep BrarAffiliated withDepartment of Medicine, Columbia University College of Physicians and Surgeons
  • , Ann R. LeeAffiliated withDepartment of Medicine, Columbia University College of Physicians and Surgeons
  • , Suzanne K. LewisAffiliated withDepartment of Medicine, Columbia University College of Physicians and Surgeons
  • , Govind BhagatAffiliated withDepartment of Medicine, Columbia University College of Physicians and Surgeons
  • , Peter H. R. GreenAffiliated withDepartment of Medicine, Columbia University College of Physicians and SurgeonsHerbert Irving Pavilion Email author 

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Abstract

Celiac disease is generally under diagnosed in the United States and it is unclear whether the disease is encountered in ethnic minorities. Our purpose is to describe a case series of African-American patients with celiac disease. Nine (1.3%) African-American patients with celiac disease were identified from a prospectively generated database of 700 patients with biopsy proven celiac disease and seen between 1981 and 2004. Females predominated, with seven, compared to two males. Diarrhea was the presentation in only two patients, while three presented with iron deficiency anemia. One third had at least one autoimmune disease. Compliance with a gluten-free diet, the only medical therapy of this disease, was poor. Only four patients adhered strictly to the diet. Celiac disease occurs in African-Americans and may well be underdiagnosed. Special attention needs to be given to methods that encourage adherence to the diet in minority groups.

Keywords:

African-American Celiac disease Compliance Gluten-free diet HLA DQ typing