Cognitive Therapy and Research

, Volume 31, Issue 2, pp 235–262

Neurobehavioral Therapies in the 21st Century: Summary of an Emerging Field and an Extended Example of Cognitive Control Training for Depression

  • Greg J. Siegle
  • Frank Ghinassi
  • Michael E. Thase
Original Article

DOI: 10.1007/s10608-006-9118-6

Cite this article as:
Siegle, G.J., Ghinassi, F. & Thase, M.E. Cogn Ther Res (2007) 31: 235. doi:10.1007/s10608-006-9118-6

Abstract

The promise of a new generation of therapies targeted to address neurobiological mechanisms thought to underlie psychological disorders, particularly depression, using cognitive and behavioral techniques is discussed. Relationships between such neurobehaviorally focused therapies and other psychological and rehabilitative interventions are also discussed. Their potential utility as adjuncts to conventional treatment, and the importance of multi-method assessment in their evaluation are emphasized. Finally, initial data from a neurobehavioral “cognitive control training” (CCT) adjunctive intervention for severe unipolar depression is presented as an extended example. These data suggest that CCT aids in reducing both physiological mechanisms underlying depression as well as depressive symptomatology.

Key words

DepressionTherapyNeurosciencefMRI

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Greg J. Siegle
    • 1
    • 2
  • Frank Ghinassi
    • 1
  • Michael E. Thase
    • 1
    • 3
  1. 1.Department of PsychiatryUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Western Psychiatric Institute and ClinicPittsburghUSA
  3. 3.University of PennsylvaniaPhiladelphiaUSA