Chemistry of Heterocyclic Compounds

, Volume 49, Issue 4, pp 561–565

One-pot assembly of 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines from pyrrolecarbo-nitriles and hydrazine

Authors

  • T. E. Glotova
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
  • D. A. Shabalin
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
  • M. Yu. Dvorko
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
  • I. A. Ushakov
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
  • E. Yu. Schmidt
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
  • A. V. Ivanov
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
  • A. I. Mikhaleva
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
    • A. E. Favorsky Irkutsk Institute of ChemistrySiberian Branch of the Russian Academy of Sciences
Article

DOI: 10.1007/s10593-013-1282-5

Cite this article as:
Glotova, T.E., Shabalin, D.A., Dvorko, M.Y. et al. Chem Heterocycl Comp (2013) 49: 561. doi:10.1007/s10593-013-1282-5

The reaction of pyrrole-2-carbonitriles with hydrazine hydrate in the presence of hydrazine dihydrochloride (ethylene glycol, 130-132°С, 1-2 h, argon atmosphere) affords the hitherto unknown 3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amines in up to 86% yield.

Keywords

3,5-bis(1H-pyrrol-2-yl)-4H-1,2,4-triazol-4-amineshydrazine hydrate1H-pyrrole-2-carbo-nitriles

Copyright information

© Springer Science+Business Media New York 2013