Drosophila telomeres: the non-telomerase alternative
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- Melnikova, L. & Georgiev, P. Chromosome Res (2005) 13: 431. doi:10.1007/s10577-005-0992-7
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In most eukaryotes, telomeres are composed of simple repetitive sequences renewable by telomerase. By contrast, Drosophila telomeres comprise arrays of non-LTR retrotransposons HeT-A, TART, and TAHRE belonging to three different families. However, closer inspection reveals that the two quite different telomere systems share quite a few components and regulatory circuits. Here we present the current knowledge on Drosophila telomeres and discuss the possible mechanisms of telomere length control.