Brief Communication

Cell and Tissue Banking

, Volume 13, Issue 1, pp 9-13

First online:

Development of a data entry auditing protocol and quality assurance for a tissue bank database

  • Matloob KhushiAffiliated withBreast Cancer Tissue Bank, The University of Sydney at the Westmead Millennium Institute Email author 
  • , Jane E. CarpenterAffiliated withBreast Cancer Tissue Bank, The University of Sydney at the Westmead Millennium Institute
  • , Rosemary L. BalleineAffiliated withBreast Cancer Tissue Bank, The University of Sydney at the Westmead Millennium InstituteTranslational Oncology, Western Sydney Local Health NetworkWestmead Institute for Cancer Research, The University of Sydney at the Westmead Millennium Institute
  • , Christine L. ClarkeAffiliated withBreast Cancer Tissue Bank, The University of Sydney at the Westmead Millennium InstituteTranslational Oncology, Western Sydney Local Health NetworkWestmead Institute for Cancer Research, The University of Sydney at the Westmead Millennium Institute

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Human transcription error is an acknowledged risk when extracting information from paper records for entry into a database. For a tissue bank, it is critical that accurate data are provided to researchers with approved access to tissue bank material. The challenges of tissue bank data collection include manual extraction of data from complex medical reports that are accessed from a number of sources and that differ in style and layout. As a quality assurance measure, the Breast Cancer Tissue Bank (http:​\\www.​abctb.​org.​au) has implemented an auditing protocol and in order to efficiently execute the process, has developed an open source database plug-in tool (eAuditor) to assist in auditing of data held in our tissue bank database. Using eAuditor, we have identified that human entry errors range from 0.01% when entering donor’s clinical follow-up details, to 0.53% when entering pathological details, highlighting the importance of an audit protocol tool such as eAuditor in a tissue bank database. eAuditor was developed and tested on the Caisis open source clinical-research database; however, it can be integrated in other databases where similar functionality is required.

Keywords

eAuditor Caisis Quality control protocol Auditing BCTB