Cancer and Metastasis Reviews

, Volume 25, Issue 3, pp 481–491

Inflammation and disease progression


    • Wayne State University School of Medicine
  • Kenneth V. Honn
    • Departments of Radiation Oncology, Pathology, and ChemistryWayne State University School of Medicine

DOI: 10.1007/s10555-006-9016-0

Cite this article as:
Krishnamoorthy, S. & Honn, K.V. Cancer Metastasis Rev (2006) 25: 481. doi:10.1007/s10555-006-9016-0


Inflammation is a physiological response to a foreign organism such as bacteria, dust particles, and viruses. Recent studies have enlightened the role of inflammation in the progression of a variety of diseases such as cancer, atherosclerosis, asthma, and psoriasis. This article is a brief overview of the inflammatory processes involved in the progression of these common diseases. Knowledge about these mechanisms can shed light into development of newer therapeutic agents that are aimed at the eradication of these diseases.



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© Springer Science + Business Media B.V. 2006