The International Journal of Cardiovascular Imaging

, Volume 29, Issue 2, pp 489–496

Fully automated right ventricular volumetry from ECG-gated coronary CT angiography data: evaluation of prototype software

  • Thomas Lehnert
  • Anna Wrzesniak
  • Dominik Bernhardt
  • Hanns Ackermann
  • J. Matthias Kerl
  • Fernando Vega-Higuera
  • Thomas J. Vogl
  • Ralf W. Bauer
Original Paper

DOI: 10.1007/s10554-012-0109-2

Cite this article as:
Lehnert, T., Wrzesniak, A., Bernhardt, D. et al. Int J Cardiovasc Imaging (2013) 29: 489. doi:10.1007/s10554-012-0109-2

Abstract

Enlargement and dysfunction of the right ventricle (RV) is a sign and outcome predictor of many cardiopulmonary diseases. Due to the complex geometry of the RV exact volumetry is cumbersome and time-consuming. We evaluated the performance of prototype software for fully automated RV segmentation and volumetry from cardiac CT data. In 50 retrospectively ECG-gated coronary CT angiography scans the endsystolic (RVVmin) and enddiastolic (RVVmax) volume of the right ventricle was calculated fully automatically by prototype software. Manual slice segmentation by two independent radiologists served as the reference standard. Measurement periods were compared for both methods. RV volumes calculated with the software were in strong agreement with the results from manual slice segmentation (Bland–Altman r = 0.95–0.98; p < 0.001; Lin’s correlation Rho = 0.87–0.96, p < 0.001) for RVVmax and RVVmin with excellent interobserver agreement between both radiologists (r = 0.97; p < 0.001). The measurement period was significantly shorter with the software (153 ± 9 s) than with manual slice segmentation (658 ± 211 s). The prototype software demonstrated very good performance in comparison to the reference standard. It promises robust RV volume results and minimizes postprocessing time.

Keywords

Right ventricle Volumetry Functional cardiac CT Prototype software Automated segmentation 

Copyright information

© Springer Science+Business Media, B.V. 2012

Authors and Affiliations

  • Thomas Lehnert
    • 1
  • Anna Wrzesniak
    • 1
  • Dominik Bernhardt
    • 2
  • Hanns Ackermann
    • 3
  • J. Matthias Kerl
    • 1
  • Fernando Vega-Higuera
    • 2
  • Thomas J. Vogl
    • 1
  • Ralf W. Bauer
    • 1
  1. 1.Department of Diagnostic and Interventional RadiologyClinic of the Goethe UniversityFrankfurtGermany
  2. 2.Computed Tomography and Radiation OncologySiemens AG Healthcare SectorForchheimGermany
  3. 3.Department of Biostatistics and Mathematic ModellingClinic of the Goethe UniversityFrankfurtGermany

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