Cancer Causes & Control

, Volume 25, Issue 9, pp 1239–1240

Erratum to: Exposure to pesticides and the risk of childhood brain tumors

  • Kathryn R. Greenop
  • Susan Peters
  • Helen D. Bailey
  • Lin Fritschi
  • John Attia
  • Rodney J. Scott
  • Deborah C. Glass
  • Nicholas H. de Klerk
  • Frank Alvaro
  • Bruce K. Armstrong
  • Elizabeth Milne
Erratum

DOI: 10.1007/s10552-014-0418-y

Cite this article as:
Greenop, K.R., Peters, S., Bailey, H.D. et al. Cancer Causes Control (2014) 25: 1239. doi:10.1007/s10552-014-0418-y
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Erratum to: Cancer Causes Control (2013) 24:1269–1278 DOI 10.1007/s10552-013-0205-1

After publication, it was noted by the authors that the dataset used for the analyses of occupational exposures in this study accidentally used incomplete occupational histories collected for 94 control fathers and 104 control mothers recruited in 2006, and these control parents were all treated as unexposed to occupational pesticides.

Results in Tables 1–3 and Supplemental Tables 1 and 2 (and the first three rows of Supplemental Table 3) of our published paper were unaffected by this error as they concerned household, rather than occupational pesticide exposure. The conclusions regarding the association with household exposure to professional pest control treatments are consequently unchanged.

However, for occupational exposure, 18 control fathers and 2 control mothers were mistakenly classified as being unexposed to pesticides when they should have been classified as exposed (any time before the child’s birth). The analyses presented in Table 4 and parts of Supplemental Table 3 in the published manuscript were re-run using the full dataset to ensure correct exposure assignment (5 case fathers and 4 control fathers were additionally excluded from revised occupational analysis due to genuinely missing data). The updated Table 4 and Supplemental Table 3 (occupational estimates only) are presented in this erratum.
Table 4

Paternal occupational exposure to pesticides and risk of childhood brain tumors

 

n Cases/controls

ORa

95 % CI

Not exposed any time before the pregnancy

201/680

1.0

Referent

Exposed any time before the pregnancy

32/103

1.07

0.68, 1.68

Exposed in the year before pregnancy

13/37

1.11

0.55, 2.23

a Adjusting for matching variables: child age, sex, state of residence, year of birth group, parental education, child’s ethnicity, fathers age, maternal and paternal occupational diesel exhaust exposure

Our original results for paternal occupational pesticide exposures were imprecise, and we concluded that these results were less clear than for household exposure but suggestive of a positive association. The revised ORs for paternal occupational exposure to pesticides are attenuated and offer little or no evidence of an increased risk. Our imputation analysis (Supplemental Table 3) still shows that these results were unlikely to be affected by bias due to missing job histories.

The sentence in the abstract concerning fathers’ occupational exposure should now read

“The OR for paternal occupational exposure in the year before the child’s conception was 1.11 (95 % CI: 0.55, 2.23).” There were still too few occupationally exposed mothers to analyse (2 cases/16 controls).

The authors offer their sincere apologies for any confusion that may have caused.

Supplementary Table 3: Paternal occupational pesticide exposure and the risk of childhood brain tumors, with controls with missing exposure data imputed

 

Exposure  % from available controls with IRSD in the same range as those controls missing data

% exposure applied to missing controls

ORa

95 % CI

Paternal occupational exposure any time before birth

13.3 %

1.08

0.72, 1.62

Paternal occupational exposure in the year before pregnancy

4.9 %

1.16

0.62, 2.14

aWith 1,467 controls, those with missing data imputed in R with ORs adjusted for child age, sex, state, year of birth group and IRSD. IRSD: Index of relative socioeconomic disadvantage, OR: odds ratio; CI: confidence interval

Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Kathryn R. Greenop
    • 1
  • Susan Peters
    • 2
  • Helen D. Bailey
    • 1
  • Lin Fritschi
    • 10
  • John Attia
    • 3
    • 4
  • Rodney J. Scott
    • 4
    • 5
  • Deborah C. Glass
    • 6
  • Nicholas H. de Klerk
    • 1
  • Frank Alvaro
    • 7
    • 8
  • Bruce K. Armstrong
    • 9
  • Elizabeth Milne
    • 1
  1. 1.Telethon Kids InstituteUniversity of Western AustraliaWest PerthAustralia
  2. 2.Western Australian Institute for Medical ResearchUniversity of Western AustraliaPerthAustralia
  3. 3.Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public HealthUniversity of NewcastleNewcastleAustralia
  4. 4.Hunter Medical Research Institute, School of Biomedical Sciences, Faculty of HealthUniversity of NewcastleNewcastleAustralia
  5. 5.Hunter Area Pathology ServiceHNEHealthNewcastleAustralia
  6. 6.Department of Epidemiology and Preventive MedicineMonash UniversityMelbourneAustralia
  7. 7.Department of Paediatric OncologyJohn Hunter Children’s HospitalNewcastleAustralia
  8. 8.School of Medicine and Public HealthUniversity of NewcastleCallaghanAustralia
  9. 9.Sydney School of Public HealthUniversity of SydneySydneyAustralia
  10. 10.Department of Epidemiology and BiostatisticsCurtin UniversityPerthAustralia

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