Cancer Causes & Control

, Volume 25, Issue 3, pp 283–291

Exposure to household painting and floor treatments, and parental occupational paint exposure and risk of childhood brain tumors: results from an Australian case–control study

  • Kathryn R. Greenop
  • Susan Peters
  • Lin Fritschi
  • Deborah C. Glass
  • Lesley J. Ashton
  • Helen D. Bailey
  • Rodney J. Scott
  • John Daubenton
  • Nicholas H. de Klerk
  • Bruce K. Armstrong
  • Elizabeth Milne
Original paper

DOI: 10.1007/s10552-013-0330-x

Cite this article as:
Greenop, K.R., Peters, S., Fritschi, L. et al. Cancer Causes Control (2014) 25: 283. doi:10.1007/s10552-013-0330-x

Abstract

Purpose

Childhood brain tumors (CBT) are the leading cause of cancer death in children, yet their etiology remains largely unknown. This study investigated whether household exposure to paints and floor treatments and parental occupational painting were associated with CBT risk in a population-based case–control study conducted between 2005 and 2010.

Methods

Cases were identified through all ten Australian pediatric oncology centers, and controls via nationwide random-digit dialing, frequency matched to cases on age, sex, and state of residence. Data were obtained from parents in mailed questionnaires and telephone interviews. Information on domestic painting and floor treatments, and parental occupational exposure to paint, in key periods relating to the index pregnancy and childhood was obtained for 306 cases and 950 controls. Data were analyzed using unconditional logistic regression, adjusting for frequency matching variables and potential confounders.

Results

Overall, we found little evidence that parental, fetal, or childhood exposure to home painting or floor treatments was associated with risk of CBT. There was, though, some evidence of a positive association between childhood exposure to indoor painting and risk of high-grade glioma [odds ratio (OR) 3.31, 95 % confidence interval (CI) 1.29, 8.52] based on very small numbers. The OR for the association between CBT and paternal occupational exposure to paint any time before the pregnancy was 1.32 (95 % CI 0.90, 1.92), which is consistent with the results of other studies.

Conclusions

Overall, we found little evidence of associations between household exposure to paint and the risk of CBT in any of the time periods investigated.

Keywords

ChildBrain tumorsPaintCase–controlSolventsOccupational exposuresHousehold exposures

Abbreviations

CBT

Childhood brain tumors

ALL

Acute lymphoblastic leukemia

CATI

Computer-assisted telephone interview

OR

Odds ratio

CI

Confidence interval

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Kathryn R. Greenop
    • 1
  • Susan Peters
    • 2
  • Lin Fritschi
    • 2
  • Deborah C. Glass
    • 3
  • Lesley J. Ashton
    • 4
  • Helen D. Bailey
    • 1
    • 5
  • Rodney J. Scott
    • 6
    • 7
    • 8
  • John Daubenton
    • 9
  • Nicholas H. de Klerk
    • 1
  • Bruce K. Armstrong
    • 10
  • Elizabeth Milne
    • 1
  1. 1.Telethon Institute for Child Health Research, Centre for Child Health ResearchUniversity of Western AustraliaPerthAustralia
  2. 2.Western Australian Institute for Medical ResearchUniversity of Western AustraliaPerthAustralia
  3. 3.Department of Epidemiology and Preventive MedicineMonash UniversityMelbourneAustralia
  4. 4.School of Women and Children’s HealthUniversity of New South WalesSydneyAustralia
  5. 5.Section of Environment and RadiationInternational Agency for Research on CancerLyonFrance
  6. 6.School of Biomedical Sciences and Pharmacy, Faculty of HealthUniversity of NewcastleNewcastleAustralia
  7. 7.Hunter Medical Research InstituteJohn Hunter HospitalNewcastleAustralia
  8. 8.Hunter Area Pathology ServiceHNEHealthNewcastleAustralia
  9. 9.Division of Women’s, Adolescent and Children’s Services (WACS)Royal Hobart HospitalHobartAustralia
  10. 10.Sydney School of Public HealthUniversity of SydneySydneyAustralia