Cancer Causes & Control

, Volume 24, Issue 12, pp 2217–2229

Racial disparities in red meat and poultry intake and breast cancer risk

  • Urmila Chandran
  • Gary Zirpoli
  • Gregory Ciupak
  • Susan E. McCann
  • Zhihong Gong
  • Karen Pawlish
  • Yong Lin
  • Kitaw Demissie
  • Christine B. Ambrosone
  • Elisa V. Bandera
Original paper

DOI: 10.1007/s10552-013-0299-5

Cite this article as:
Chandran, U., Zirpoli, G., Ciupak, G. et al. Cancer Causes Control (2013) 24: 2217. doi:10.1007/s10552-013-0299-5

Abstract

Purpose

Research on the role of red meat and poultry consumption in breast carcinogenesis is inconclusive, but the evidence in African-American (AA) women is lacking. The association between consuming meat and breast cancer risk was examined in the Women’s Circle of Health Study involving 803 AA cases, 889 AA controls, 755 Caucasian cases, and 701 Caucasian controls.

Methods

Dietary information was collected using a Food Frequency Questionnaire. Odds ratios (OR) and 95 % confidence intervals (CI) were obtained from logistic regression models adjusting for potential covariates.

Results

Comparing the fourth versus the first quartiles, among Caucasian women, processed meat (OR = 1.48; 95 % CI 1.07–2.04), unprocessed red meat (OR = 1.40; 95 % CI 1.01–1.94), and poultry intakes (OR = 1.42; 95 % CI 1.01–1.99) increased breast cancer risk. Risk associated with poultry intake was more dominant in premenopausal women (OR = 2.33; 95 % CI 1.44–3.77) and for women with ER− tumors (OR = 2.55; 95 % CI 1.29–5.03) in the Caucasian group. Associations in AA women were mostly null except for a significant increased risk trend with processed meat consumption for ER+ tumors (OR = 1.36; 95 % CI 0.94–1.97, p trend = 0.04).

Conclusions

Overall, associations between breast cancer risk and consumption of red meat and poultry were of different magnitude in AA and Caucasian women, with further differences noted by menopausal and hormone receptor status in Caucasian women. This is the first study to examine racial differences in meat and breast cancer risk and represents some of the first evidence in AA women.

Keywords

Meat African-American Breast cancer Poultry Race Estrogen receptor 

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Urmila Chandran
    • 1
    • 2
  • Gary Zirpoli
    • 3
  • Gregory Ciupak
    • 3
  • Susan E. McCann
    • 3
  • Zhihong Gong
    • 3
  • Karen Pawlish
    • 4
  • Yong Lin
    • 1
    • 2
  • Kitaw Demissie
    • 1
    • 2
  • Christine B. Ambrosone
    • 3
  • Elisa V. Bandera
    • 1
    • 2
  1. 1.Rutgers Cancer Institute of New JerseyRobert Wood Johnson Medical SchoolNew BrunswickUSA
  2. 2.Rutgers School of Public HealthPiscatawayUSA
  3. 3.Roswell Park Cancer InstituteBuffaloUSA
  4. 4.New Jersey State Cancer RegistryNew Jersey Department of HealthTrentonUSA

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