Cancer Causes & Control

, Volume 22, Issue 3, pp 479–485

Papillary thyroid cancer incidence rates vary significantly by birthplace in Asian American women

  • Pamela L. Horn-Ross
  • Laura A. McClure
  • Ellen T. Chang
  • Christina A. Clarke
  • Theresa H. M. Keegan
  • Rudolph P. Rull
  • Thu Quach
  • Scarlett Lin Gomez
Original paper

DOI: 10.1007/s10552-010-9720-5

Cite this article as:
Horn-Ross, P.L., McClure, L.A., Chang, E.T. et al. Cancer Causes Control (2011) 22: 479. doi:10.1007/s10552-010-9720-5

Abstract

Objective

To investigate how birthplace influences the incidence of papillary thyroid cancer among Asian American women.

Methods

Birthplace- and ethnic-specific age-adjusted and age-specific incidence rates were calculated using data from the California Cancer Registry for the period 1988–2004. Birthplace was statistically imputed for 30% of cases using a validated imputation method based on age at Social Security number issuance. Population estimates were obtained from the US Census. Incidence rate ratios (IRR) and 95% confidence intervals (CI) were estimated for foreign-born vs. US-born women.

Results

Age-adjusted incidence rates of papillary thyroid cancer among Filipina (13.7 per 100,000) and Vietnamese (12.7) women were more than double those of Japanese women (6.2). US-born Chinese (IRR = 0.48, 95% CI: 0.40–0.59) and Filipina women (IRR = 0.74, 95% CI: 0.58–0.96) had significantly higher rates than those who were foreign-born; the opposite was observed for Japanese women (IRR = 1.55, 95% CI: 1.17–2.08). The age-specific patterns among all foreign-born Asian women and US-born Japanese women showed a slow steady increase in incidence until age 70. However, among US-born Asian women (except Japanese), substantially elevated incidence rates during the reproductive and menopausal years were evident.

Conclusions

Ethnic- and birthplace-variation in papillary thyroid cancer incidence can provide insight into the etiology of this increasingly common and understudied cancer.

Keywords

Papillary thyroid cancerIncidence ratesBirthplaceAsian American womenCancer surveillance

Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Pamela L. Horn-Ross
    • 1
    • 2
  • Laura A. McClure
    • 1
  • Ellen T. Chang
    • 1
    • 2
  • Christina A. Clarke
    • 1
    • 2
  • Theresa H. M. Keegan
    • 1
    • 2
  • Rudolph P. Rull
    • 1
    • 2
  • Thu Quach
    • 1
  • Scarlett Lin Gomez
    • 1
    • 2
  1. 1.Cancer Prevention Institute of CaliforniaFremontUSA
  2. 2.Department of Health Research and Policy and Stanford Cancer CenterStanford University School of MedicinePalo AltoUSA