Cancer Causes & Control

, Volume 21, Issue 9, pp 1467–1473

Coffee and tea consumption and endometrial cancer risk in a population-based study in New Jersey

  • Elisa V. Bandera
  • Melony G. Williams-King
  • Camelia Sima
  • Sharon Bayuga-Miller
  • Katherine Pulick
  • Homer Wilcox
  • Ann G. Zauber
  • Sara H. Olson
Original paper

DOI: 10.1007/s10552-010-9575-9

Cite this article as:
Bandera, E.V., Williams-King, M.G., Sima, C. et al. Cancer Causes Control (2010) 21: 1467. doi:10.1007/s10552-010-9575-9

Abstract

We evaluated the role of tea and coffee and substances added (sugar/honey, creamers, and milk) on endometrial cancer risk in a population-based case–control study in six counties in New Jersey, including 417 cases and 395 controls. Multivariate odds ratios (OR) and 95% confidence intervals (CI) were computed using unconditional logistic regression. There was a moderate inverse association with coffee consumption, with an adjusted OR of 0.65 (95% CI: 0.36–1.17) for women who reported more than two cups/day of coffee compared to none. Tea consumption appeared to increase risk (OR: 1.93; 95% CI: 1.08–3.45), but after including the variables sugar/honey and cream/milk added to tea in the model, the risk estimate was attenuated and no longer statistically significant (OR: 1.77; 95% CI: 0.96–3.28 for those consuming more than one cup/day of tea compared to nonusers). There was a suggestion of a decreased risk associated with green tea, but the confidence interval included one (adjusted OR for one or more cups/week vs. none: 0.75; 95% CI: 0.48–1.18). We found an association with adding sugar/honey to tea, with those adding two or more teaspoons/cup having an OR of 2.66 (95% CI: 1.42–4.98; p for trend <0.01) after adjusting for relevant confounders. For sugar/honey added to coffee the corresponding OR was 1.43 (95% CI: 0.81–2.55). Our results indicate that sugars and milk/cream added to coffee and tea should be considered in future studies evaluating coffee and tea and endometrial cancer risk.

Keywords

Endometrial cancerDietNutritionCoffeeTeaSugar

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Elisa V. Bandera
    • 1
    • 2
  • Melony G. Williams-King
    • 1
    • 2
  • Camelia Sima
    • 3
  • Sharon Bayuga-Miller
    • 3
  • Katherine Pulick
    • 3
  • Homer Wilcox
    • 4
  • Ann G. Zauber
    • 3
  • Sara H. Olson
    • 3
  1. 1.The Cancer Institute of New Jersey, Robert Wood Johnson Medical SchoolNew BrunswickUSA
  2. 2.School of Public HealthUniversity of Medicine and Dentistry of New JerseyPiscatawayUSA
  3. 3.Department of Epidemiology and BiostatisticsMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  4. 4.New Jersey Department of Health and Senior ServicesTrentonUSA