Cancer Causes & Control

, Volume 21, Issue 2, pp 269–274

Increasing trend of the incidence of esophageal squamous cell carcinoma, but not adenocarcinoma, in Taiwan

  • Ching-Liang Lu
  • Hui-Chu Lang
  • Jiing-Chyuan Luo
  • Chun-Chu Liu
  • Han-Chieh Lin
  • Full-Young Chang
  • Shou-Dong Lee
Original paper

DOI: 10.1007/s10552-009-9458-0

Cite this article as:
Lu, CL., Lang, HC., Luo, JC. et al. Cancer Causes Control (2010) 21: 269. doi:10.1007/s10552-009-9458-0
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Abstract

Epidemiologic data on esophageal cancer in Asia are extremely limited. We examined temporal trends in the incidence of esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EA) in Taiwan. Patients with esophageal cancer were identified from the Taiwan Cancer Registry between 1979 and 2003. Age-standardized incidences of ESCC and EA were calculated based on the national census and world standard population. Trends in incidence rates were estimated by calculating the annual percentage change (APC). The age-standardized incidence of ESCC increased progressively (from 1979–1983 to 1999–2003: 2.63 to 4.37 per 100,000-year), with an APC higher in male (3.27%, P < 0.0001) than that in female (1.23%, P = 0.03). Though the crude incidence of EA progressively increased in both gender (male: 0.28–0.49 per 100,000-year; female 0.07–0.11 per 100,000-year), the age-standardized incidence of EA is similar along the study period with an APC of 0.72% (P = 0.20) in male and 1.59% (P = 0.30) in female. In Taiwan, the incidence of ESCC significantly increased from 1979 to 2003, whereas the incidence of EA remained unchanged. Although EA incidence has not recently increased, it could in the future.

Keywords

Esophagus cancerSquamous cell carcinomaAdenocarcinomaTaiwan

Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Ching-Liang Lu
    • 1
    • 4
    • 5
  • Hui-Chu Lang
    • 3
  • Jiing-Chyuan Luo
    • 1
    • 5
  • Chun-Chu Liu
    • 2
    • 5
  • Han-Chieh Lin
    • 1
    • 5
  • Full-Young Chang
    • 1
    • 5
  • Shou-Dong Lee
    • 1
    • 5
  1. 1.Division of GastroenterologyTaipei Veterans General HospitalTaipeiTaiwan
  2. 2.Department of MedicineKoo Foundation Sun Yat-Sen Cancer CenterTaipeiTaiwan
  3. 3.Institute of Hospital and Health Care AdministrationNational Yang-Ming UniversityTaipeiTaiwan
  4. 4.Institute of Brain ScienceNational Yang-Ming UniversityTaipeiTaiwan
  5. 5.School of MedicineNational Yang-Ming UniversityTaipeiTaiwan