Cancer Causes & Control

, Volume 20, Issue 10, pp 1881–1892

Disparities in survival after Hodgkin lymphoma: a population-based study

  • Theresa H. M. Keegan
  • Christina A. Clarke
  • Ellen T. Chang
  • Sarah J. Shema
  • Sally L. Glaser
Original paper

DOI: 10.1007/s10552-009-9382-3

Cite this article as:
Keegan, T.H.M., Clarke, C.A., Chang, E.T. et al. Cancer Causes Control (2009) 20: 1881. doi:10.1007/s10552-009-9382-3
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Abstract

Survival after Hodgkin lymphoma (HL) is generally favorable, but may vary by patient demographic characteristics. The authors examined HL survival according to race/ethnicity and neighborhood socioeconomic status (SES), determined from residential census-block group at diagnosis. For 12,492 classical HL patients ≥15 years diagnosed in California during 1988–2006 and followed through 2007, we determined risk of overall and HL-specific death using Cox proportional hazards regression; analyses were stratified by age and Ann Arbor stage. Irrespective of disease stage, patients with lower neighborhood SES had worse overall and HL-specific survival than patients with higher SES. Patients with the lowest quintile of neighborhood SES had a 64% (patients aged 15–44 years) and 36% (≥45 years) increased risk of HL-death compared to patients with the highest quintile of SES; SES results were similar for overall survival. Even after adjustment for neighborhood SES, blacks and Hispanics had increased risks of HL-death 74% and 43% (15–44 years) and 40% and 17% (≥45 years), respectively, higher than white patients. The racial/ethnic differences in survival were evident for all stages of disease. These data provide evidence for substantial, and probably remediable, racial/ethnic and neighborhood SES disparities in HL outcomes.

Keywords

Hodgkin diseaseSurvivalMortalitySocial classCensus

Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Theresa H. M. Keegan
    • 1
  • Christina A. Clarke
    • 1
  • Ellen T. Chang
    • 1
  • Sarah J. Shema
    • 1
  • Sally L. Glaser
    • 1
  1. 1.Northern California Cancer CenterFremontUSA