Cancer Causes & Control

, Volume 20, Issue 2, pp 163–170

Tobacco smoking and chewing as risk factors for multiple human papillomavirus infections and cervical squamous intraepithelial lesions in two countries (Côte d’Ivoire and Finland) with different tobacco exposure

  • Aline Simen-Kapeu
  • Guy La Ruche
  • Vesa Kataja
  • Merja Yliskoski
  • Christine Bergeron
  • Apollinaire Horo
  • Kari Syrjänen
  • Seppo Saarikoski
  • Matti Lehtinen
  • François Dabis
  • Annie J. Sasco
Original Paper

DOI: 10.1007/s10552-008-9230-x

Cite this article as:
Simen-Kapeu, A., La Ruche, G., Kataja, V. et al. Cancer Causes Control (2009) 20: 163. doi:10.1007/s10552-008-9230-x

Abstract

Our objective was to compare the association between tobacco smoking and chewing and the risk of multiple human papillomavirus (HPV) infections and cervical squamous intraepithelial lesions (SILs) in two populations with different tobacco exposure. We studied 2,162 women from Côte d’Ivoire, West Africa, and 419 women from Finland, Northern Europe, with baseline data on cervical screening, HPV DNA status and smoking and chewing habits. The proportion of women who smoked and/or chewed tobacco was higher in Finland (36.8%) than in Côte d’Ivoire (3.7%), where tobacco chewing (2.6%) was more common than tobacco smoking (1.4%). Having multiple HPV infections was common in HPV16 and/or 18-infected women (60.4% in Finland and 47.2% in Côte d’Ivoire). There was no increased risk of multiple HPV infections among tobacco consumers. We found that women ≥30 years of age exposed to tobacco through smoking in Finland (OR: 2.2, 95% CI: 0.5–8.7) and chewing in Côte d’Ivoire (OR: 5.5, 95% CI: 2.1–14) had a moderately or highly increased risk of high-grade SIL, respectively. In the latter, the risk was statistically significant. Our findings emphasize the need for health initiatives targeted to prevent tobacco smoking or chewing among women especially in less industrialized countries.

Keywords

Tobacco smoking Tobacco chewing Cervical SIL Multiple HPV infections 

Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Aline Simen-Kapeu
    • 1
  • Guy La Ruche
    • 2
  • Vesa Kataja
    • 3
    • 4
  • Merja Yliskoski
    • 5
  • Christine Bergeron
    • 6
  • Apollinaire Horo
    • 7
  • Kari Syrjänen
    • 8
  • Seppo Saarikoski
    • 9
  • Matti Lehtinen
    • 1
    • 10
  • François Dabis
    • 11
  • Annie J. Sasco
    • 11
  1. 1.Department of Child and Adolescent HealthNational Public Health InstituteOuluFinland
  2. 2.Programme National de Lutte Contre le SIDAAbidjanCôte d’Ivoire
  3. 3.Department of OncologyKuopio University HospitalKuopioFinland
  4. 4.Vaasa Central HospitalVaasaFinland
  5. 5.Central Hospital of Central FinlandJyväskyläFinland
  6. 6.Laboratoire Pasteur-CerbaCergy-Pontoise, ParisFrance
  7. 7.Département de Gynécologie et ObstétriqueCentre Hospitalier et Universitaire de YopougonAbidjanCôte d’Ivoire
  8. 8.Turku University HospitalTurkuFinland
  9. 9.Department of Obstetrics and GynaecologyKuopio University HospitalKuopioFinland
  10. 10.School of Public HealthUniversity of TampereTampereFinland
  11. 11.Unité INSERM 897Université Victor Segalen Bordeaux 2BordeauxFrance

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